PLD4
Identifiers
Aliases	PLD4, C14orf175, phospholipase D family member 4
External IDs	OMIM:618488;MGI:2144765;HomoloGene:16350;GeneCards:PLD4;OMA:PLD4 - orthologs
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q32.33 Start 104,924,713bp[1] End 104,937,761bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 F1 Start 112,727,089bp[2] End 112,735,424bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte monocyte C1 segment bone marrow cells testicle spleen substantia nigra appendix right hemisphere of cerebellum Hypothalamus Top expressed in spleen white matter of cerebellum bone marrow granulocyte zone of skin white adipose tissue thymus lung jejunum ileum More reference expression data BioGPS n/a
Gene ontology Molecular function phospholipase D activity N-acylphosphatidylethanolamine-specific phospholipase D activity catalytic activity hydrolase activity phosphatidylinositol phospholipase C activity Cellular component integral component of membrane endoplasmic reticulum membrane membrane nucleus endoplasmic reticulum trans-Golgi network membrane phagocytic vesicle Biological process lipid catabolic process inositol phosphate metabolic process lipid metabolism hematopoietic progenitor cell differentiation phagocytosis Sources:Amigo /QuickGO
Orthologs Species Human Mouse Entrez 122618 104759 Ensembl ENSG00000166428 ENSMUSG00000052160 UniProt Q96BZ4 Q8BG07 RefSeq (mRNA) NM_001308174 NM_138790 NM_178911 RefSeq (protein) NP_001295103 NP_620145 NP_849242 Location (UCSC) Chr 14: 104.92 – 104.94 Mb Chr 12: 112.73 – 112.74 Mb PubMed search [3] [4]
Wikidata
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Phospholipase D family member 4 is anenzyme that in humans is encoded by the PLD4gene.^[5][6]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

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