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PGRMC2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
PGRMC2
Identifiers
AliasesPGRMC2, DG6, PMBP, progesterone receptor membrane component 2
External IDsOMIM:607735;MGI:1918054;HomoloGene:38169;GeneCards:PGRMC2;OMA:PGRMC2 - orthologs
Gene location (Human)
Chromosome 4 (human)
Chr.Chromosome 4 (human)[1]
Chromosome 4 (human)
Genomic location for PGRMC2
Genomic location for PGRMC2
Band4q28.2Start128,269,237bp[1]
End128,288,829bp[1]
Gene location (Mouse)
Chromosome 3 (mouse)
Chr.Chromosome 3 (mouse)[2]
Chromosome 3 (mouse)
Genomic location for PGRMC2
Genomic location for PGRMC2
Band3|3 BStart41,020,761bp[2]
End41,037,481bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • jejunal mucosa

  • islet of Langerhans

  • stromal cell of endometrium

  • epithelium of colon

  • skin of abdomen

  • skin of arm

  • skin of leg

  • adipose tissue

  • rectum

  • abdominal fat
Top expressed in
  • otic placode

  • saccule

  • supraoptic nucleus

  • otic vesicle

  • motor neuron

  • yolk sac

  • skin of external ear

  • Epithelium of choroid plexus

  • seminal vesicula

  • decidua
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

10424

70804

Ensembl

ENSG00000164040

ENSMUSG00000049940

UniProt

O15173

Q80UU9

RefSeq (mRNA)

NM_006320

NM_027558

RefSeq (protein)

NP_006311

NP_081834

Location (UCSC)Chr 4: 128.27 – 128.29 MbChr 3: 41.02 – 41.04 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Progesterone receptor membrane component 2 (abbreviatedPGRMC2) is aprotein which is encoded by thePGRMC2gene.[5][6] It has been detected in theplacenta,liver, andspermatozoa, among other areas.[5][6]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000164040 –Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000049940 –Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^abGerdes D, Wehling M, Leube B, Falkenstein E (1998). "Cloning and tissue expression of two putative steroid membrane receptors".Biol. Chem.379 (7):907–11.doi:10.1515/bchm.1998.379.7.907.PMID 9705155.
  6. ^abLösel R, Breiter S, Seyfert M, Wehling M, Falkenstein E (2005). "Classic and non-classic progesterone receptors are both expressed in human spermatozoa".Horm. Metab. Res.37 (1):10–4.doi:10.1055/s-2005-861023.PMID 15702432.
PRTooltip Progesterone receptor
Agonists
Mixed
(SPRMsTooltip Selective progesterone receptor modulators)
Antagonists
mPRTooltip Membrane progesterone receptor
(PAQRTooltip Progestin and adipoQ receptor)
Agonists
Antagonists


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