In March 2016 the company announced a chemistry upgrade to its nanopore sequencing product 'R9', using a protein nanopore in collaboration with the laboratory of Han Remaut (VIB/Vrije Universiteit Brussel).[9] The company stated in a webcast that R9 is designed to improve error rates and yield.[10]
American astronautKate Rubins with a MinION sequencer on the ISS in August 2016.
In July 2016, a MinION nanopore sequencer was included on the ninth NASA/SpaceX commercial cargo resupply services mission to theInternational Space Station.[11] The aim of the mission was to provide proof of concept for the MinION's functionality in a microgravity environment.[12] During the mission, ISS crew members successfully sequenced DNA from bacteria, bacteriophage and rodents from samples prepared on Earth.[13] Maintaining the MinION device as a research facility on the space station holds the potential to support a number of additional science investigations, any of which could have Earth based applications.[14]
Top view of a closed Oxford Nanopore Technologies MinION sequencer showing how it is small enough to be held in one hand
The main products of Oxford Nanopore are:
MinION:[3][15][16] this harmonica-sized portable protein nanopore sequencing USB device has been commercially available since May 2015[17] after having been launched initially through an early access program, the MinION Access Program (MAP).[18]
GridION X5: this desktop device has been commercially available since March 2017.[19] The device processes up to five MinION Flow Cells and enables generation of up to 100 Gb of data per run.[20]
PromethION: this desktop, high throughput device will be available through an access program[21] that opened for registration in July 2015. The device contains channels for 144,000 nanopores (in comparison to MinION’s 512).[22]
VolTRAX: this device is designed for automated library preparation so that users do not need a laboratory or lab skills to run the device.[23] Registration for the early access program was opened in October 2016.[24]
Metrichor: this spinout company from Oxford Nanopore was set up to provide end to end solutions for biological analyses, using nanopore sensing technologies.[25][26]
SmidgION: a mobile phone sequencer announced in May 2016, currently in development.[27]
^McIntyre, Alexa B. R.; Rizzardi, Lindsay; Yu, Angela M.; Rosen, Gail L.; Alexander, Noah; Botkin, Douglas J.; John, Kristen K.; Castro-Wallace, Sarah L.; Burton, Aaron S. (10 December 2015). "Nanopore Sequencing in Microgravity".bioRxiv10.1101/032342.
£183.2 million (2024)[1]
