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Otto Fritz Meyerhof

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Otto Fritz Meyerhof
Born(1884-04-12)12 April 1884
Died6 October 1951(1951-10-06) (aged 67)
Philadelphia,Pennsylvania, United States
EducationUniversity of Strasbourg
University of Heidelberg
University of Berlin
Known forRelationship between the consumption of oxygen and themetabolism oflactic acid in the muscle
AwardsNobel Prize in Physiology or Medicine, 1922[1]
Scientific career
FieldsPhysics andBiochemistry
InstitutionsUniversity of Kiel
German biochemist (1884–1951)

Otto Fritz Meyerhof (German pronunciation:[ˈɔtoˈmaɪɐhoːf]; 12 April 1884 – 6 October 1951) was a Germanphysician andbiochemist who won the 1922Nobel Prize in Physiology and Medicine.[2][3]

Biography

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Otto Fritz Meyerhof was born inHannover, at Theaterplatz 16A (now:Rathenaustrasse 16A),[4][5] the son of wealthyJewish parents. In 1888, his family moved toBerlin, where Otto spent most of his childhood, and where he started his study ofmedicine. He continued these studies inStrasbourg andHeidelberg, from which he graduated in 1909, with a work titled "Contributions to the Psychological Theory of Mental Illness".

In Heidelberg, he met Hedwig Schallenberg. They married in 1914 and had three children together: a daughter, Bettina, and two sons, Gottfried (who after emigration used the anglicized name Geoffrey) and Walter.

In 1912, Otto Meyerhof moved to theUniversity of Kiel, where he received a professorship in 1918. In 1922, he was awarded theNobel Prize in Medicine, withArchibald Vivian Hill, for his work on muscle metabolism, includingglycolysis.[6] In 1929, he became one of the directors of theKaiser Wilhelm Institute for Medical Research in Heidelberg, a position he held until 1938, when Jews were expelled from university teaching positions.

To escape the increasing oppression of Jews by theNazi regime, in 1938 Meyerhof emigrated with his family to Paris.[7] After the fall of France in 1940, they fled to Marseille. Aided by theEmergency Rescue Committee, they left the country by ship to the United States that year. Meyerhof was appointed to a guest professorship at theUniversity of Pennsylvania in Philadelphia.

Meyerhof died inPhiladelphia at the age of 67.[8] In addition to receiving the Nobel Prize, he was recognized for his contributions to the study of glycolysis, by the naming of the common series of reactions for the pathway inEukaryotes as theEmbden–Meyerhof–Parnas Pathway.[9]

See also

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References

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  1. ^Raju, T. N. (1998)."The Nobel chronicles. 1922: Archibald Vivian Hill (1886-1977), Otto Fritz Meyerhof (1884-1951)".Lancet.352 (9137): 1396.doi:10.1016/S0140-6736(05)60805-7.PMID 9802314.S2CID 54412926.
  2. ^Anon (1951). "Obituary: Otto Fritz Meyerhof".The Lancet.258 (6687):790–792.doi:10.1016/S0140-6736(51)91682-0.PMID 14874513.
  3. ^"The Nobel Prize in Physiology or Medicine 1922".Nobel Prize. Retrieved11 January 2011.
  4. ^Walter Selke and Christian Heppner,The family of the Nobel Prize recipient Otto Meyerhof in Hannover, in: Hannoversche Geschichtsblaetter 71 (2017), p.156-166;ISBN 978-3-86525-602-7
  5. ^"Uni Kiel – Otto Fritz Meyerhof". Uni-kiel.de. Retrieved26 June 2017.
  6. ^Kresge, N.; Simoni, R. D.; Hill, R. L. (2005)."Otto Fritz Meyerhof and the elucidation of the glycolytic pathway".The Journal of Biological Chemistry.280 (4): e3.doi:10.1016/S0021-9258(20)76366-0.PMID 15665335.
  7. ^Jean-Marc Chouraqui, Gilles Dorival, Colette Zytnicki,Enjeux d'Histoire, Jeux de Mémoire: les Usages du Passé Juif, Maisonneuve & Larose, 2006, p. 548[1]
  8. ^"Dr. Meyerhof, Winner Of 1923 Nobel Prize".The New York Times. 8 October 1951. Retrieved11 January 2011.
  9. ^Barnett JA (April 2003)."A history of research on yeasts 5: the fermentation pathway".Yeast.20 (6):509–43.doi:10.1002/yea.986.PMID 12722184.S2CID 26805351.

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