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| Industry | pharmaceutical |
|---|---|
| Founded | 1931 |
| Defunct | 1993; 32 years ago (1993) |
| Fate | Merged withMcNeil Pharmaceuticals in the US andJanssen Pharmaceutica in Canada (Both are nowJohnson & Johnson) |
| Successors | McNeil Pharmaceuticals in the US andJanssen Pharmaceutica in Canada later both becameJohnson & Johnson |
Area served | United States |
Ortho Pharmaceutical was initially formed in theUnited States in 1931 as asubsidiary ofJohnson & Johnson to market the firstprescriptionspermicidal contraceptive jelly,Ortho-Gynol.
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In the 1940s, Ortho introduced thecoil-springdiaphragm, and assisted in the development of thePapanicolaou smear stain toscreen forcervical cancer.
In 1963, Ortho introduced the secondoral contraceptive available in the United States (Ortho-Novum 10 andOrtho-Novum 2, produced bySyntex).
In 1964, Ortho bought rights to and marketed theGynekoil (Margulies Coil) andLippes Loop inert plasticIUDs in the United States until the mid-1970s and 1985, respectively.
In 1968, Ortho introducedRhoGAM Rho(D) immune globulin, the first medication developed to preventRhhemolytic disease of the newborn.
In 1973, Ortho and Syntex introduced the firstprogestogen only pills (mini-pills) available in the United States,Mirconor andNor-QD.
In 1982, Ortho introduced the firstbiphasic oral contraceptive available in the United States,Ortho-Novum 10/11.
In 1984, Ortho introduced the firsttriphasic oral contraceptive available in the United States,Ortho-Novum 7/7/7.
In 1989, theFDA approvedOrtho Cyclen containing the first newprogestin (norgestimate) approved in over 20 years in the United States.
In 1992, Ortho introducedOrtho Tri-Cyclen in the United States, which in 1996 became the first oral contraceptive with an FDA-approved non-contraceptiveindication (treatment of moderateacne).
From 1995 to 2003, Ortho marketed theParaGard copper T-380A IUD in the United States.
In 2001, Ortho introduced theOrtho Evratransdermalcontraceptive patch in the United States.
In 1993, Ortho Pharmaceutical merged withMcNeil Pharmaceutical in 1993 to formOrtho-McNeil Pharmaceutical.
InCanada, Ortho Products began operations inMontreal in 1941. The company started with one product and three employees and it was one of the first companies in Canada to make oral contraceptives. Moving toToronto in 1944, the company outgrew a number of rented facilities until its own facilities were constructed in 1955. Continued growth required a number of plant expansions. Ortho Pharmaceutical Canada merged withMcNeil Pharmaceutical Canada in 1991, and merged withJanssen Pharmaceutica Canada in 1995 to form Janssen-Ortho.