Movatterモバイル変換

[0]ホーム
URL:

Jump to content
WikipediaThe Free Encyclopedia
Search

OUP-16

From Wikipedia, the free encyclopedia
OUP-16
Names
IUPAC name
1-cyano-3-[[(2R,5R)-5-(1H-imidazol-5-yl)oxolan-2-yl]methyl]-2-methylguanidine
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C11H16N6O/c1-13-11(16-6-12)15-4-8-2-3-10(18-8)9-5-14-7-17-9/h5,7-8,10H,2-4H2,1H3,(H,14,17)(H2,13,15,16)/t8-,10-/m1/s1
    Key: CCOQWVUQXNRKKP-PSASIEDQSA-N
  • CN=C(NC[C@H]1CC[C@@H](O1)C2=CN=CN2)NC#N
Properties
C11H16N6O
Molar mass248.290 g·mol−1
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
☒N (what is checkY☒N ?)
Chemical compound
This articlemay be too technical for most readers to understand. Pleasehelp improve it tomake it understandable to non-experts, without removing the technical details.(March 2021) (Learn how and when to remove this message)
icon
This articleneeds additional citations forverification. Please helpimprove this article byadding citations to reliable sources. Unsourced material may be challenged and removed.
Find sources: "OUP-16" – news ·newspapers ·books ·scholar ·JSTOR(March 2021) (Learn how and when to remove this message)

OUP-16 is ahistamine agonist selective for theH4 subtype.[1]

References

[edit]
  1. ^Hashimoto, T; Harusawa, S; Araki, L; Zuiderveld, OP; Smit, MJ; Imazu, T; Takashima, S; Yamamoto, Y; Sakamoto, Y; Kurihara, T; Leurs, R; Bakker, RA; Yamatodani, A (July 2003). "A Selective Human H4-Receptor Agonist: (−)-2-Cyano-1-methyl-3-{(2R,5R)-5- [1H-imidazol-4(5)-yl]tetrahydrofuran-2-yl}methylguanidine".Journal of Medicinal Chemistry.46 (14):3162–5.doi:10.1021/jm0300025.PMID 12825954.
H1
Agonists
Antagonists
H2
Agonists
Antagonists
H3
Agonists
Antagonists
H4
Agonists
Antagonists
Stub icon

Thispharmacology-related article is astub. You can help Wikipedia byadding missing information.

Retrieved from "https://en.wikipedia.org/w/index.php?title=OUP-16&oldid=1019067196"
Categories:
Hidden categories:
[8]ページ先頭
©2009-2026 Movatter.jp