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OR7A5

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
OR7A5
Identifiers
AliasesOR7A5, HTPCR2, olfactory receptor family 7 subfamily A member 5
External IDsMGI:1333808;HomoloGene:133620;GeneCards:OR7A5;OMA:OR7A5 - orthologs
Gene location (Human)
Chromosome 19 (human)
Chr.Chromosome 19 (human)[1]
Chromosome 19 (human)
Genomic location for OR7A5
Genomic location for OR7A5
Band19p13.12Start14,826,241bp[1]
End14,835,185bp[1]
Gene location (Mouse)
Chromosome 10 (mouse)
Chr.Chromosome 10 (mouse)[2]
Chromosome 10 (mouse)
Genomic location for OR7A5
Genomic location for OR7A5
Band10|10 C1Start78,864,575bp[2]
End78,872,108bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • inferior olivary nucleus

  • C1 segment

  • corpus epididymis

  • substantia nigra

  • pituitary gland

  • anterior pituitary

  • caput epididymis

  • skin of leg

  • inferior ganglion of vagus nerve

  • internal globus pallidus
Top expressed in
  • lung

  • embryo

  • spermatid

  • Mesencephalon
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

26659

18357

Ensembl

ENSG00000188269

ENSMUSG00000060205

UniProt

Q15622

Q8VGU7

RefSeq (mRNA)

NM_017506
NM_001370480
NM_001370481
NM_001370482
NM_001370483

NM_147041

RefSeq (protein)

NP_059976
NP_001357409
NP_001357410
NP_001357411
NP_001357412

NP_667252

Location (UCSC)Chr 19: 14.83 – 14.84 MbChr 10: 78.86 – 78.87 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 7A5 is aprotein that in humans is encoded by theOR7A5gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000188269Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000060205Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ab"Entrez Gene: OR7A5 olfactory receptor, family 7, subfamily A, member 5".

Further reading

[edit]

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


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