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OR5P3

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
OR5P3
Identifiers
AliasesOR5P3, JCG1, olfactory receptor family 5 subfamily P member 3
External IDsMGI:3030342;HomoloGene:72039;GeneCards:OR5P3;OMA:OR5P3 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for OR5P3
Genomic location for OR5P3
Band11p15.4Start7,824,818bp[1]
End7,830,840bp[1]
Gene location (Mouse)
Chromosome 7 (mouse)
Chr.Chromosome 7 (mouse)[2]
Chromosome 7 (mouse)
Genomic location for OR5P3
Genomic location for OR5P3
Band7|7 E3Start108,229,201bp[2]
End108,230,835bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • skin of abdomen

  • skin of leg

  • urinary bladder

  • lactiferous gland
    n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

120066

258769

Ensembl

ENSG00000182334
ENSG00000280808
ENSG00000278253

ENSMUSG00000063764

UniProt

Q8WZ94

Q8VG42

RefSeq (mRNA)

NM_153445

NM_146773

RefSeq (protein)

NP_703146

NP_666984

Location (UCSC)Chr 11: 7.82 – 7.83 MbChr 7: 108.23 – 108.23 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 5P3 is aprotein that in humans is encoded by theOR5P3gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

Ligands

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The OR5P3 receptor is associated with examples of ligands includes:[6][7]

  • 1-octanol
  • celery ketone
  • (-)-carvone

See also

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References

[edit]
  1. ^abcENSG00000280808, ENSG00000278253 GRCh38: Ensembl release 89: ENSG00000182334, ENSG00000280808, ENSG00000278253Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000063764Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ab"Entrez Gene: OR5P3 olfactory receptor, family 5, subfamily P, member 3".
  6. ^Audouze K, Tromelin A, Le Bon AM, Belloir C, Petersen RK, Kristiansen K, et al. (2014)."Identification of odorant-receptor interactions by global mapping of the human odorome".PLOS ONE.9 (4): e93037.Bibcode:2014PLoSO...993037A.doi:10.1371/journal.pone.0093037.PMC 3973694.PMID 24695519.
  7. ^Sanz G, Thomas-Danguin T, Hamdani EH, Le Poupon C, Briand L, Pernollet JC, et al. (September 2008)."Relationships between molecular structure and perceived odor quality of ligands for a human olfactory receptor".Chemical Senses.33 (7):639–53.doi:10.1093/chemse/bjn032.PMID 18603653.

Further reading

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External links

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This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13
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