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OR4M1

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
OR4M1
Identifiers
AliasesOR4M1, OR14-7, olfactory receptor family 4 subfamily M member 1
External IDsMGI:3030568;HomoloGene:51759;GeneCards:OR4M1;OMA:OR4M1 - orthologs
Gene location (Human)
Chromosome 14 (human)
Chr.Chromosome 14 (human)[1]
Chromosome 14 (human)
Genomic location for OR4M1
Genomic location for OR4M1
Band14q11.2Start19,773,504bp[1]
End19,783,696bp[1]
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)[2]
Chromosome 14 (mouse)
Genomic location for OR4M1
Genomic location for OR4M1
Band14|14 C1Start50,553,963bp[2]
End50,564,218bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • right testis

  • left testis

  • bone marrow
Top expressed in
  • respiratory epithelium

  • nasal epithelium

  • peripheral nervous system

  • olfactory epithelium
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

441670

258658

Ensembl

ENSG00000176299

ENSMUSG00000045306

UniProt

Q8NGD0

Q8VFT4

RefSeq (mRNA)

NM_001005500

NM_146664

RefSeq (protein)

NP_001005500

NP_666875

Location (UCSC)Chr 14: 19.77 – 19.78 MbChr 14: 50.55 – 50.56 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 4M1 is aprotein that in humans is encoded by theOR4M1gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000176299Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000045306Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ab"Entrez Gene: OR4M1 olfactory receptor, family 4, subfamily M, member 1".

Further reading

[edit]

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13
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