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OR4C6

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
OR4C6
Identifiers
AliasesOR4C6, OR11-138, olfactory receptor family 4 subfamily C member 6
External IDsMGI:3031064;HomoloGene:81570;GeneCards:OR4C6;OMA:OR4C6 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for OR4C6
Genomic location for OR4C6
Band11q11Start55,662,201bp[1]
End55,666,195bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for OR4C6
Genomic location for OR4C6
Band2|2 E1Start89,126,695bp[2]
End89,127,612bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • lymph node

  • prostate

  • tonsil
Top expressed in
  • respiratory epithelium

  • sensory nervous system

  • body proper

  • sensory organ

  • nasal epithelium

  • olfactory epithelium
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

219432

258785

Ensembl

ENSG00000181903

ENSMUSG00000075094

UniProt

Q8NH72

Q8VG58

RefSeq (mRNA)

NM_001004704

NM_146789

RefSeq (protein)

NP_001004704

NP_667000

Location (UCSC)Chr 11: 55.66 – 55.67 MbChr 2: 89.13 – 89.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 4C6 is aprotein that in humans is encoded by theOR4C6gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000181903Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000075094Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ab"Entrez Gene: OR4C6 olfactory receptor, family 4, subfamily C, member 6".

Further reading

[edit]

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13
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