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OR2M7

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
OR2M7
Identifiers
AliasesOR2M7, OR1-58, olfactory receptor family 2 subfamily M member 7
External IDsOMIM:618509;HomoloGene:133839;GeneCards:OR2M7;OMA:OR2M7 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for OR2M7
Genomic location for OR2M7
Band1q44Start248,323,630bp[1]
End248,324,568bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • primary visual cortex
    n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

391196

n/a

Ensembl

ENSG00000177186

n/a

UniProt

Q8NG81

n/a

RefSeq (mRNA)

NM_001004691

n/a

RefSeq (protein)

NP_001004691

n/a

Location (UCSC)Chr 1: 248.32 – 248.32 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Olfactory receptor 2M7 is aprotein that in humans is encoded by theOR2M7gene.[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[3]

Ligands

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Agonists include:[4]

See also

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References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000177186Ensembl, May 2017
  2. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ab"Entrez Gene: OR2M7 olfactory receptor, family 2, subfamily M, member 7".
  4. ^Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD (March 2009)."Odor coding by a Mammalian receptor repertoire".Science Signaling.2 (60): ra9.doi:10.1126/scisignal.2000016.PMC 2774247.PMID 19261596.

Further reading

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External links

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This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13
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