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OR2L2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
OR2L2
Identifiers
AliasesOR2L2, HSHTPCRH07, HTPCRH07, OR1-48, OR2L12, OR2L4P, olfactory receptor family 2 subfamily L member 2
External IDsMGI:3030001;HomoloGene:78689;GeneCards:OR2L2;OMA:OR2L2 - orthologs
Gene location (Human)
Chromosome 1 (human)
Chr.Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for OR2L2
Genomic location for OR2L2
Band1q44Start248,030,070bp[1]
End248,042,305bp[1]
Gene location (Mouse)
Chromosome 16 (mouse)
Chr.Chromosome 16 (mouse)[2]
Chromosome 16 (mouse)
Genomic location for OR2L2
Genomic location for OR2L2
Band16|16 A3Start19,328,308bp[2]
End19,341,016bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • gonad

  • C1 segment

  • prefrontal cortex

  • ganglionic eminence

  • substantia nigra

  • primary visual cortex

  • hippocampus proper

  • testicle

  • putamen

  • Hypothalamus
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

26246

258937

Ensembl

ENSG00000203663

ENSMUSG00000045341

UniProt

Q8NH16

Q8VGJ5

RefSeq (mRNA)

NM_001004686
NM_001385855

NM_146935

RefSeq (protein)

NP_001004686

NP_667146

Location (UCSC)Chr 1: 248.03 – 248.04 MbChr 16: 19.33 – 19.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2L2 is aprotein that in humans is encoded by theOR2L2gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000203663Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000045341Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells".Nature.355 (6359):453–5.Bibcode:1992Natur.355..453P.doi:10.1038/355453a0.PMID 1370859.S2CID 43926.
  6. ^ab"Entrez Gene: OR2L2 olfactory receptor, family 2, subfamily L, member 2".

Further reading

[edit]

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13
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