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OR2J2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
OR2J2
Identifiers
AliasesOR2J2, OR6-19, OR6-8, OR6.3.8, ORL684, dJ80I19.4, hs6M1-6, olfactory receptor family 2 subfamily J member 2
External IDsMGI:2177520;HomoloGene:88922;GeneCards:OR2J2;OMA:OR2J2 - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for OR2J2
Genomic location for OR2J2
Band6p22.1Start29,170,907bp[1]
End29,175,811bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for OR2J2
Genomic location for OR2J2
Band17|17 B1Start38,614,418bp[2]
End38,618,461bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • uterine tube

  • right testis

  • left testis

  • appendix

  • hippocampus proper

  • Hypothalamus

  • caudate nucleus
    n/a
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

26707

258481

Ensembl

ENSG00000204700

ENSMUSG00000054940

UniProt

O76002

Q8VFC2

RefSeq (mRNA)

NM_030905

NM_146488

RefSeq (protein)

NP_112167

NP_666699

Location (UCSC)Chr 6: 29.17 – 29.18 MbChr 17: 38.61 – 38.62 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2J2 is aprotein that in humans is encoded by theOR2J2gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

Ligands

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Agonists include:[6]

See also

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References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000204700Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000054940Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ab"Entrez Gene: OR2J2 olfactory receptor, family 2, subfamily J, member 2".
  6. ^Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD (March 2009)."Odor coding by a Mammalian receptor repertoire".Science Signaling.2 (60): ra9.doi:10.1126/scisignal.2000016.PMC 2774247.PMID 19261596.

Further reading

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External links

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This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
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Family 8
Family 9
Family 10
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Family 13
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