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OR2H2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
OR2H2
Identifiers
AliasesOR2H2, FAT11, OLFR2, OLFR42B, OR2H3, dJ271M21.2, hs6M1-12, olfactory receptor family 2 subfamily H member 2
External IDsOMIM:600578;MGI:2177473;HomoloGene:68546;GeneCards:OR2H2;OMA:OR2H2 - orthologs
Gene location (Human)
Chromosome 6 (human)
Chr.Chromosome 6 (human)[1]
Chromosome 6 (human)
Genomic location for OR2H2
Genomic location for OR2H2
Band6p22.1Start29,585,121bp[1]
End29,590,500bp[1]
Gene location (Mouse)
Chromosome 17 (mouse)
Chr.Chromosome 17 (mouse)[2]
Chromosome 17 (mouse)
Genomic location for OR2H2
Genomic location for OR2H2
Band17|17 B1Start37,394,763bp[2]
End37,399,391bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • testicle

  • putamen

  • nucleus accumbens

  • caudate nucleus

  • right hemisphere of cerebellum

  • ventricular zone

  • Temporal Lobe

  • Amygdala

  • hippocampus proper

  • anterior cingulate cortex
Top expressed in
  • embryo

  • blastocyst

  • bone marrow

  • conceptus

  • female reproductive system

  • placenta
More reference expression data
BioGPS


More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

7932

258469

Ensembl

ENSG00000204657

ENSMUSG00000056600

UniProt

O95918

n/a

RefSeq (mRNA)

NM_007160

NM_146477

RefSeq (protein)

NP_009091

n/a

Location (UCSC)Chr 6: 29.59 – 29.59 MbChr 17: 37.39 – 37.4 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2H2 is aprotein that in humans is encoded by theOR2H2gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000204657Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000056600Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ab"Entrez Gene: OR2H2 olfactory receptor, family 2, subfamily H, member 2".

Further reading

[edit]

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


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