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OR2F1

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
OR2F1
Identifiers
AliasesOR2F1, OLF3, OR14-60, OR2F3, OR2F3P, OR2F4, OR2F5, OR7-139, OR7-140, 7M1-2, olfactory receptor family 2 subfamily F member 1 (gene/pseudogene), olfactory receptor family 2 subfamily F member 1
External IDsOMIM:608497;MGI:3030287;HomoloGene:128151;GeneCards:OR2F1;OMA:OR2F1 - orthologs
Gene location (Human)
Chromosome 7 (human)
Chr.Chromosome 7 (human)[1]
Chromosome 7 (human)
Genomic location for OR2F1
Genomic location for OR2F1
Band7q35Start143,954,844bp[1]
End143,997,312bp[1]
Gene location (Mouse)
Chromosome 6 (mouse)
Chr.Chromosome 6 (mouse)[2]
Chromosome 6 (mouse)
Genomic location for OR2F1
Genomic location for OR2F1
Band6|6 B2.1Start42,716,305bp[2]
End42,723,897bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • tibial arteries

  • apex of heart

  • smooth muscle tissue

  • sural nerve

  • placenta

  • anterior cingulate cortex

  • ascending aorta

  • Descending thoracic aorta

  • appendix

  • right coronary artery
    n/a
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

26211

258016

Ensembl

ENSG00000284866
ENSG00000213215

ENSMUSG00000095831

UniProt

Q13607

Q7TRV7

RefSeq (mRNA)

NM_012369

NM_001011799

RefSeq (protein)

NP_036501

NP_001011799

Location (UCSC)Chr 7: 143.95 – 144 MbChr 6: 42.72 – 42.72 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 2F1 is aprotein that in humans is encoded by theOR2F1gene.[5][6]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[6]

See also

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References

[edit]
  1. ^abcENSG00000213215 GRCh38: Ensembl release 89: ENSG00000284866, ENSG00000213215Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000095831Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome".Nat Genet.18 (3):243–50.doi:10.1038/ng0398-243.PMID 9500546.S2CID 31129045.
  6. ^ab"Entrez Gene: OR2F1 olfactory receptor, family 2, subfamily F, member 1".

Further reading

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External links

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This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


Class I
(fish-like receptors)
Family 51
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Class II
(tetrapod specific receptors)
Family 1
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