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OR1S2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
OR1S2
Identifiers
AliasesOR1S2, OR11-231, olfactory receptor family 1 subfamily S member 2
External IDsMGI:3031330;GeneCards:OR1S2;OMA:OR1S2 - orthologs
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for OR1S2
Genomic location for OR1S2
Band11q12.1Start58,203,202bp[1]
End58,204,142bp[1]
Gene location (Mouse)
Chromosome 19 (mouse)
Chr.Chromosome 19 (mouse)[2]
Chromosome 19 (mouse)
Genomic location for OR1S2
Genomic location for OR1S2
Band19|19 AStart13,755,242bp[2]
End13,760,284bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • thoracic aorta

  • ascending aorta
Top expressed in
  • embryo

  • respiratory epithelium

  • nasal epithelium

  • olfactory epithelium
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

219958

258991

Ensembl

ENSG00000197887

ENSMUSG00000048356

UniProt

Q8NGQ3

B9EHG2

RefSeq (mRNA)

NM_001004459

NM_146989

RefSeq (protein)

NP_001004459

NP_667200

Location (UCSC)Chr 11: 58.2 – 58.2 MbChr 19: 13.76 – 13.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 1S2 is aprotein that in humans is encoded by theOR1S2gene.[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

[edit]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000197887Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000048356Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ab"Entrez Gene: OR1S2 olfactory receptor, family 1, subfamily S, member 2".

Further reading

[edit]

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.


Class I
(fish-like receptors)
Family 51
Family 52
Family 56
Class II
(tetrapod specific receptors)
Family 1
Family 2
Family 3
Family 4
Family 5
Family 6
Family 7
Family 8
Family 9
Family 10
Family 11
Family 12
Family 13


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