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Nutritional science (alsonutrition science, sometimes shortnutrition, datedtrophology[1]) is thescience that studies the physiological process ofnutrition (primarilyhuman nutrition), interpreting thenutrients and other substances infood in relation to maintenance, growth,reproduction,health anddisease of anorganism.[2]
Before nutritional science emerged as an independent study disciplines, mainlychemists worked in this area. The chemical composition of food was examined.Macronutrients, especiallyprotein,fat andcarbohydrates, have been the focus components of the study of (human) nutrition since the 19th century. Until the discovery ofvitamins and vital substances, the quality of nutrition was measured exclusively by the intake ofnutritional energy.

The early years of the 20th century were summarized by Kenneth John Carpenter in hisShort History of Nutritional Science as "the vitamin era".[3] The first vitamin was isolated and chemically defined in 1926 (thiamine). The isolation ofvitamin C followed in 1932 and its effects on health, the protection againstscurvy, was scientifically documented for the first time.[4]
At the instigation of the British physiologistJohn Yudkin at theUniversity of London, the degrees Bachelor of Science and Master of Science in nutritional science were established in the 1950s.[5]
Nutritional science as a separate discipline was institutionalized in Germany in November 1956 whenHans-Diedrich Cremer was appointed to the chair for human nutrition in Giessen. The Institute for Nutritional Science was initially located at the Academy for Medical Research and Further Education, which was transferred to the Faculty of Human Medicine when theJustus Liebig University was reopened. Over time, seven other universities with similar institutions followed in Germany.[6]
From the 1950s to 1970s, a focus of nutritional science was ondietary fat andsugar. From the 1970s to the 1990s, attention was put on diet-related chronic diseases andsupplementation.[4]
Nutritional science is often combined withfood science (nutrition and food science).
Trophology is a term used globally for nutritional science in other languages, in English the term is dated. Today, it is partly still used for the approach offood combining that advocates specific combinations (or advises against certain combinations) of food.Ecotrophology is a branch of nutritional science concerned with everyday practice and elements from household management that is primarily studied in Germany.
Nutritional science as a subject is taught at universities around the world. At the beginning of the programs, the basic subjects of biology, chemistry, mathematics and physics are part of the curriculum. Later, a focus is oninorganic chemistry, functional biology,biochemistry andgenetics. At most universities, students can specialize in certain areas, this involves subjects such as special food chemistry, nutritionalphysiology,nutritional epidemiology,food law andnutritional medicine. Students who are more interested in the economic aspect usually specialize in the field of food economics. Laboratory exercises are also on the curriculum at most universities.