| Nottingham Arabidopsis Stock Centre | |
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| Website | https://arabidopsis.info |
TheNottingham Arabidopsis Stock Centre (NASC) provides seed and information resources to the International ArabidopsisGenome Project and the wider research community. It is based in the School of Biosciences at theUniversity of Nottingham'sSutton Bonington Campus, in the English county ofNottinghamshire.
It holds more than 800,000 different stocks of seed representing nearly a milliongenotypes and provided aGenechip service from 2002-2013. Newly generated research stocks,mutants orlines of Arabidopsis thaliana are donated as samples to NASC where they are maintained and thus are made available to scientists worldwide.
Established in 1990[1][2] as part of the Plant Molecular Biology initiative of the Agricultural and Food Research Council (AFRC), the Centre is currently funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and theUniversity of Nottingham.
The Stock Centre was founded by Dr Bernard Mulligan; Directed from 1991 to 1999 by Dr Mary Anderson and from 1999–present by Prof. Sean Tobias May.
NASC's activities are coordinated with those of the Arabidopsis Biological Resource Center, (ABRC) based atOhio State University, USA. This facilitates a unified and efficient service for the research community.
The stock centres have a distribution agreement. NASC distributes toEurope and ABRC distributes tothe Americas. Laboratories in other locations may establish their primary affiliation with either centre.
When NASC started in 1990 it inherited hundreds of stocks from the Arabidopsis Information Service (AIS) - Started by Robbelen in 1965 and continued by Burger (1971), Kranz (1978), and Kranz and Kirchheim (1981, 1987), the AIS donated its complement of stocks listed in the 24th edition of the AIS stock book.[3] Stock numbers held at NASC/ABRC in the 1990s then increased steadily by many hundreds mainly due to new technologies of mass transformation (e.g. seed transformation by Ken Feldmann, University of Arizona); but also due to many new mutagenesis programs encouraged by the development of Arabidopsis as a major model organism accompanied by generous donations of seed from many international members of the community.
In 1999 NASC received a large influx of thousands of stocks generated through T-DNA transformation and donated by Pelletier and Bechtold fromINRA. This was the first of many very large populations that came out of the community and which took the complement of stocks held by the stock centres into the hundreds of thousands. The largest (most populous) seed donations have been theGABI-kat lines from Germanyvia Bernd Weisshaar;[4] and the SALK lines from Joe Ecker.[5] Between them, these two populations account for more than half of all stocks held by the stock centres today.
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