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Nordinone

From Wikipedia, the free encyclopedia
Nordinone
Names
IUPAC name
11α-Hydroxy-10,17,17-trimethylgonane-4,13-dien-3-one
Systematic IUPAC name
(3bR,9aR,9bS,10R)-10-Hydroxy-1,1,9a-trimethyl-1,2,3,3b,4,5,8,9,9a,9b,10,11-dodecahydro-7H-cyclopenta[a]phenanthren-7-one
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C20H28O2/c1-19(2)8-7-14-15-5-4-12-10-13(21)6-9-20(12,3)18(15)17(22)11-16(14)19/h10,15,17-18,22H,4-9,11H2,1-3H3/t15-,17+,18+,20-/m0/s1
    Key: ALFAUJVLIRDQGD-MMTROXRISA-N
  • C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@@H](CC4=C3CCC4(C)C)O
Properties
C20H28O2
Molar mass300.442 g·mol−1
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
Chemical compound

Nordinone (INN), also known as11α-hydroxy-17,17-dimethyl-18-norandrosta-4,13-dien-3-one, is anaturally occurringsteroid withantiandrogen properties isolated as ametabolite from thefungusMonocillium nordinii.[1][2]

References

[edit]
  1. ^J. Elks (14 November 2014).The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 647–.ISBN 978-1-4757-2085-3.
  2. ^Aver, William A.; Peña-Rodriguez, Luis (1987). "Minor metabolites of Monocillium nordinii".Phytochemistry.26 (5):1353–1355.Bibcode:1987PChem..26.1353A.doi:10.1016/S0031-9422(00)81811-7.ISSN 0031-9422.


ARTooltip Androgen receptor
Agonists
SARMsTooltip Selective androgen receptor modulator
Antagonists
GPRC6A
Agonists


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