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Neuropeptides B/W receptor 2

From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
NPBWR2
Identifiers
AliasesNPBWR2, GPR8, Neuropeptides B/W receptor 2, neuropeptides B and W receptor 2
External IDsOMIM:600731;HomoloGene:128565;GeneCards:NPBWR2;OMA:NPBWR2 - orthologs
Gene location (Human)
Chromosome 20 (human)
Chr.Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for NPBWR2
Genomic location for NPBWR2
Band20q13.33Start64,103,802bp[1]
End64,107,565bp[1]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • primary visual cortex

  • superior frontal gyrus

  • prefrontal cortex

  • dorsolateral prefrontal cortex

  • Brodmann area 9

  • right frontal lobe

  • pituitary gland

  • anterior pituitary

  • anterior cingulate cortex

  • adrenal gland
    n/a
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

2832

n/a

Ensembl

ENSG00000125522
ENSG00000277339

n/a

UniProt

P48146

n/a

RefSeq (mRNA)

NM_005286

n/a

RefSeq (protein)

NP_005277

n/a

Location (UCSC)Chr 20: 64.1 – 64.11 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Neuropeptides B/W receptor 2, also known asNPBW2, is a humanprotein encoded by the NPBWR2gene.[3]

The protein encoded by this gene is an integral membrane protein and G protein-coupled receptor. The encoded protein is similar in sequence to another G protein-coupled receptor (GPR7), and it is structurally similar to opioid and somatostatin receptors. This protein binds neuropeptides B and W. This gene is intronless and is expressed primarily in the frontal cortex of the brain.[3]

See also

[edit]

References

[edit]
  1. ^abcENSG00000277339 GRCh38: Ensembl release 89: ENSG00000125522, ENSG00000277339Ensembl, May 2017
  2. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ab"Entrez Gene: NPBWR2 neuropeptides B/W receptor 2".

Further reading

[edit]

External links

[edit]

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

Neurotransmitter
Adrenergic
Purinergic
Serotonin
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Metabolites and
signaling molecules
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Peptide
Neuropeptide
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Miscellaneous
Taste, bitter
Orphan
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Taste, sweet
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