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Eunice Kennedy Shriver National Institute of Child Health and Human Development

Coordinates:39°0′12″N77°6′16″W / 39.00333°N 77.10444°W /39.00333; -77.10444
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US National Institutes of Health unit
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Eunice Kennedy Shriver National Institute of Child Health and Human Development
Map
Agency overview
Formed1962 (1962)
Agency executive
Parent agencyNational Institutes of Health
Websitewww.nichd.nih.gov

TheEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) is one of theNational Institutes of Health (NIH) in theUnited States Department of Health and Human Services. It supports and conductsresearch aimed at improving the health of children, adults, families, and communities, including:

History

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The impetus for NICHD came from the Task Force on the Health and Well-Being of Children, convened in 1961 and led by Dr. Robert E. Cooke, a senior medical advisor to PresidentJohn F. Kennedy.Eunice Kennedy Shriver also served on the task force, which reported that more research was needed on the physical, emotional, and intellectual growth of children.

TheU.S. Congress established NICHD in 1962 as the first NIH institute to focus on the entire life process rather than on a specific disease or body system. NICHD became a funding source for research on birth defects and intellectual and developmental disabilities (IDDs), created a new pediatrics specialty, and established IDDs as a field of research. The institute also focused on the idea that adult health has its origins in early development and that behavior and social science were important aspects of human development.[2]

On December 21, 2007, by act of Congress (Public Law 110–54), NICHD was renamed theEunice Kennedy Shriver National Institute of Child Health and Human Development in honor of Mrs. Shriver's vision, dedication, and contributions to the founding of the institute.[3]

Past directors

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Past directors from 1963–present:[4]

No.PortraitDirectorTook officeLeft officeRefs.
1Robert A. AldrichMarch 1, 1963October 1964
2Donald HartingJuly 8, 19651966
3Gerald D. LaVeckOctober 9, 1966September 1, 1973
ActingGilbert L. WoodsideSeptember 1, 1973September 1, 1974
4Norman KretchmerSeptember 1, 1974September 30, 1981
ActingBetty H. PickettSeptember 30, 1981June 30, 1982
5Mortimer B. LipsettJuly 1, 1982January 7, 1985
6Duane AlexanderFebruary 5, 1986September 30, 2009
ActingSusan ShurinOctober 1, 2009November 30, 2009[5]
ActingAlan Edward GuttmacherDecember 1, 2009July 21, 2010[6]
7July 22, 2010September 30, 2015[7][8]
ActingCatherine Y. SpongOctober 1, 2015October 31, 2016[9]
8Diana W. BianchiNovember 1, 2016April 2025[10]
ActingAlison CernichApril 2025Present[11]

Mission

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Themission of NICHD is to ensure that every person is born healthy and wanted, that women suffer no harmful effects from reproductive processes, and that all children have the chance to achieve their full potential for healthy and productive lives, free from disease or disability, and to ensure the health, productivity, independence, and well-being of all people through optimal rehabilitation.[12]

Operation

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As of November 2016, the director of NICHD isDiana W. Bianchi.[13]

NICHD's budget in 2015 was an estimated $1.3 billion, which supported research at institutions, universities, and organizations throughout the world, as well as research conducted by NICHD scientists on the NIH campus in Bethesda, MD, and at other facilities.

Components

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Source:[14]

  • Office of the Director
  • Division of Extramural Research
    • Child Development and Behavior Branch
    • Contraceptive Discovery and Development Branch
    • Developmental Biology and Structural Variation Branch
    • Fertility and Infertility Branch
    • Gynecologic Health and Disease Branch
    • Intellectual and Developmental Disabilities Branch
    • Maternal and Pediatric Infectious Disease Branch
    • Obstetric and Pediatric Pharmacology and Therapeutics Branch
    • Pediatric Growth and Nutrition Branch
    • Pediatric Trauma and Critical Illness Branch
    • Population Dynamics Branch
    • Pregnancy and Perinatology Branch
  • National Center for Medical Rehabilitation Research
  • Division of Intramural Population Health Research
    • Biostatistics and Bioinformatics Branch
    • Epidemiology Branch
    • Health Behavior Branch
  • Division of Intramural Research
    • Office of the Scientific Director
    • Scientific Affinity Groups
      • Aquatic Models of Human Development
      • Basic Mechanisms of Genome Regulation
      • Behavioral Determinants and Developmental Imaging
      • Bone and Matrix Biology in Development and Disease
      • Cell and Structural Biology
      • Cell Regulation and Development
      • Developmental Endocrine Oncology and Genetics
      • Genetics and Epigenetics of Development
      • Integrative Membrane, Cell, and Tissue Pathophysiology
      • Metals Biology and Molecular Medicine
      • Neurosciences
      • Pediatric Endocrinology, Metabolism, and Molecular Genetics
      • Perinatal and Obstetrical Research
      • Reproductive Endocrine and Gynecology

National Children's Study

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TheNational Children's Study (NCS) was a longitudinalcohort study that planned to recruit participants from across the United States of America. The NCS was led by theNational Institutes of Health, with the NICHD serving as the scientific lead. It was intended to measure the many factors that contribute tohealth and disease from before birth through age 21. This included, but was not limited to, the search for drivers of diseases with prenatal or developmental origins. The Study was closed in December 2014.[15][16]

Organization

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Within NICHD, the NCS Program Office administered the implementation of day-to-day Study operations. The Program Office was supervised by the Study Director, Steven Hirschfeld, MD, PhD Associate Director for Clinical Research, NICHD.

For advice and recommendations regarding Study framework, content, and methodologies, the NCS Program Office engaged external advisors and scientific groups. These groups included federal partners such as the NCS Federal Advisory Committee and a Federal Consortium with representatives from multiple federal agencies including: theU.S. Department of Health and Human Services, theNational Institute of Environmental Health Sciences of the National Institutes of Health, theCenters for Disease Control and Prevention, and theU.S. Environmental Protection Agency. An independent Study Monitoring and Oversight Committee monitored study progress and participant safety.

In addition to these more formal channels, the NCS solicited feedback from subject matter experts from around the world and from individuals, community advocates, and professional societies concerned with child health. The NCS Program Office also provided public forums for input on a variety of initiatives.[17]

Congressional Mandate

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The "President's Task Force on Health Risks and Safety Risks to Children" recommended this federal initiative in 1999, after which Congress passed theChildren's Health Act of 2000 (Title X, Section 1004). The Act charged NICHD to:

  1. plan, develop, and implement aprospective cohort study, from birth to adulthood, to evaluate the effects of both chronic and intermittent exposures on child health and human development; and
  2. investigate basic mechanisms of developmental disorders and environmental factors, both risk and protective, that influence health and developmental processes.

The Act required this NCS to:

  1. incorporate behavioral, emotional, educational, and contextual consequences to enable a complete assessment of the physical, chemical, biological, and psychosocial environmental influences on children's well-being;
  2. gather data on environmental influences and outcomes on diverse populations of children, which may include the consideration of prenatal exposures; and
  3. consider health disparities among children, which may include the consideration of prenatal exposures[18]

Objective

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The NCS was designed to examine the effects of the environment—broadly defined to include factors such as air, water, diet, sound, family dynamics, community, and cultural influences— andgenetics on the growth,development, and health of children across the United States. The NCS was designed to follow approximately 100,000 children, some from before birth, through age 21 years. The NCS planned to collect comprehensive information to:

  1. contribute to improving the health and well-being of all children
  2. deepen our understanding of the contribution of various factors to a range of health and disease outcomes
  3. understand factors that lead to health disparities.

With this broad perspective, the NCS was designed to contribute to the implementation of health equity, where each individual has an opportunity to realize their health potential.[19]

Discontinued

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The NCS was in its Vanguard, orpilot phase, which was designed to assess the feasibility, acceptability, cost, and utility of Study scientific output, logistics, and operations prior to initiating the Main Study. The Vanguard Study enrolled about 5,000 children in 40 counties across the United States. General recruitment was completed in July 2013.

On December 12, 2014, the National Children's Study closed, after an expert review committee advised the NIH Director that moving forward with the larger Main Study would not be the best way to add to the understanding of how environmental and genetic factors influence child health and development.[20]

Notable accomplishments

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NICHD has made numerous contributions to improving the health of children, adults, families, and communities. Selected research advances from 2015 include improving the health of infants born preterm, encouraging healthy behaviors, and optimizing rehabilitation.[21]

See also

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Notes and references

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  1. ^"Discover the NICHD"(PDF). NICHD. December 2013.
  2. ^"Establishment of the NICHD".NICHD. RetrievedNovember 17, 2016.
  3. ^NICHD Renamed for Eunice Kennedy Shriver, Advocate for Institute's Founding
  4. ^"NICID Directors".www.nih.gov. July 9, 2015.
  5. ^"Susan Shurin, M.D., joins NICHD from National Heart, Lung, and Blood Institute (NHLBI)". NICHD. September 29, 2009.
  6. ^"NIH Appoints Alan Guttmacher Acting Director of NICHD". NICHD. December 2, 2009.
  7. ^"NIH Director Announces Appointment of Alan Guttmacher as Director of NICHD". NIH. July 22, 2010. Archived fromthe original on January 5, 2016.
  8. ^"Guttmacher retiring as director of NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development". NICHD. August 6, 2015.
  9. ^"Catherine Spong appointed NICHD Deputy Director". NICHD. September 3, 2014.
  10. ^"NIH names Dr. Diana Bianchi director of the National Institute of Child Health and Human Development". NIH. August 25, 2016. Archived fromthe original on September 23, 2016.
  11. ^Wosen, Jonathan (April 25, 2025)."NIH announces six new acting institute directors, many of them filling posts of ousted predecessors".Stat News.
  12. ^"NICHD Mission and Scientific Accomplishments".www.nichd.nih.gov. Archived fromthe original on January 12, 2013. RetrievedNovember 17, 2016.
  13. ^"NIH names Dr. Diana Bianchi director of the National Institute of Child Health and Human Development".www.nichd.nih.gov. August 25, 2016. RetrievedNovember 17, 2016.
  14. ^"Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)".National Institutes of Health (NIH). July 9, 2015. RetrievedNovember 17, 2016.
  15. ^Jocelyn Kaiser (December 12, 2014)."NIH cancels massive U.S. children's study".Science. RetrievedJuly 28, 2022.has too many flaws to be carried out in a tight budget environment, advisers today told National Institutes of Health (NIH) Director Francis Collins. He announced he is dismantling the study immediately.
  16. ^Francis S. Collins (December 12, 2014)."Statement on the National Children's Study".hih.gov. NIH. Archived fromthe original on December 17, 2014. RetrievedDecember 14, 2014.I am appointing Dr. David Murray, NIH Associate Director for Prevention, effectively immediately, to manage the orderly transition of the NCS program office and closure of the study.
  17. ^"Organization of the National Children's Study". Archived fromthe original on October 6, 2014. RetrievedSeptember 29, 2014.
  18. ^National Institutes of HealthNew Proposed Collection; Comment Request; Neuropsychosocial Measures Formative Research Methodology Studies for the National Children's Study Federal Register, vol 76, No. 84, May 2, 2011
  19. ^"Study Overview". Archived fromthe original on October 6, 2014. RetrievedSeptember 29, 2014.
  20. ^National Children's Study (NCS) Working GroupFINAL REPORT – DECEMBER 12, 2014 National Institutes of Health, Advisory Committee to the Director, 19 pages
  21. ^"Selected NICHD Research Advances of 2015".www.nichd.nih.gov. December 16, 2015. RetrievedNovember 17, 2016.

Further reading

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External links

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