Movatterモバイル変換

[0]ホーム
URL:

Jump to content
WikipediaThe Free Encyclopedia
Search

NS-398

From Wikipedia, the free encyclopedia
NS-398
Space-filling model of the NS-398 molecule
Names
Preferred IUPAC name
N-[2-(Cyclohexyloxy)-4-nitrophenyl]methanesulfonamide
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
  • InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3 checkY
    Key: KTDZCOWXCWUPEO-UHFFFAOYSA-N ☒N
  • InChI=1/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3
    Key: KTDZCOWXCWUPEO-UHFFFAOYAY
  • CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2CCCCC2
Properties
C13H18N2O5S
Molar mass314.36 g·mol−1
AppearanceOff-white solid
Insoluble
Solubility inDMSO5 mg/mL
Hazards
GHS labelling:[1]
GHS07: Exclamation mark
Warning
H302,H312,H332
P280
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Chemical compound

NS-398 is aCOX-2 inhibitor used in the study of the function ofcyclooxygenases.[2]

See also

[edit]

References

[edit]
  1. ^"N194 NS-398". Sigma-Aldrich. Retrieved13 December 2021.
  2. ^Wei Shen; Yong Li; Ying Tang; James Cummins; Johnny Huard (2005)."NS-398, a Cyclooxygenase-2-Specific Inhibitor, Delays Skeletal Muscle Healing by Decreasing Regeneration and Promoting Fibrosis".American Journal of Pathology.167 (4):1105–1117.doi:10.1016/S0002-9440(10)61199-6.PMC 1603662.PMID 16192645.
Receptor
(ligands)
DP (D2)Tooltip Prostaglandin D2 receptor
DP1Tooltip Prostaglandin D2 receptor 1
DP2Tooltip Prostaglandin D2 receptor 2
EP (E2)Tooltip Prostaglandin E2 receptor
EP1Tooltip Prostaglandin EP1 receptor
EP2Tooltip Prostaglandin EP2 receptor
EP3Tooltip Prostaglandin EP3 receptor
EP4Tooltip Prostaglandin EP4 receptor
Unsorted
FP (F2α)Tooltip Prostaglandin F receptor
IP (I2)Tooltip Prostacyclin receptor
TP (TXA2)Tooltip Thromboxane receptor
Unsorted
Enzyme
(inhibitors)
COX
(PTGS)
PGD2STooltip Prostaglandin D synthase
PGESTooltip Prostaglandin E synthase
PGFSTooltip Prostaglandin F synthase
PGI2STooltip Prostacyclin synthase
TXASTooltip Thromboxane A synthase
Others


This article about anEther is astub. You can help Wikipedia byexpanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=NS-398&oldid=1322626004"
Categories:
Hidden categories:
[8]ページ先頭
©2009-2025 Movatter.jp