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| Other names | Formylmescaline;N-Formyl-3,4,5-trimethoxyphenethylamine;N-Formyl-3,4,5-TMPEA |
| Drug class | Serotonergic psychedelic;Hallucinogen |
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| Identifiers | |
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| PubChemCID | |
| Chemical and physical data | |
| Formula | C12H17NO4 |
| Molar mass | 239.271 g·mol−1 |
| 3D model (JSmol) | |
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N-Formylmescaline, also known asN-formyl-3,4,5-trimethoxyphenethylamine, is analkaloid and possiblepsychedelic drug of thephenethylamine andscaline families related tomescaline.[1][2][3] It is theN-formylderivative of mescaline.[1][2][3]N,N-Diformylmescaline has been found to bechemically unstable underacidic orbasic conditions, breaking down intoN-formylmescaline, which then further degrades into mescaline.[1][2][3] Relatedly, it is thought thatN-formylmescaline andN,N-diformylmescaline may act asprodrugs of mescalinein vivo.[1][2][3]N-Formylmescaline is known to occur naturally in trace amounts inpeyote.[2][3][4][5][6]
In January 2020, Australian authorities seized a powder suspected of being cocaine. After analysis by GC–MS, NMR and IR, the compound was identified as N,N-diformylmescaline. Under exposure to acid and basic conditions, the structure degraded to N-formylmescaline, a naturally occurring compound in Peyote, and further to mescaline (Gallagher et al., 2023).
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