| Mucinous cystadenoma | |
|---|---|
 | |
| Micrograph showing a mucinous cystadenoma of theovary.H&E stain. | |
| Specialty | Oncology  |
Mucinous cystadenoma is abenigncystictumor lined by amucinousepithelium. It is a type of cysticadenoma (cystadenoma).
Mucinous cystadenomas arise in a number of locations; however, cases of mucinous cystadenoma at different locations are not generally considered to be related to one another.
Mucinous cystadenomas may be found in the:
Mucinous cystadenomas make up 15–20% of allovarian tumors. They often become very large and can extend up into theabdomen.
These tumors are usually evaluated usingultrasound,CT scan, orMRI. Findings on imaging studies are nonspecific. These ovarian tumors are usually multi-septated, cystic masses with thin walls. They also contain varying amounts of solidtissue which consists of proliferatingstromal tissue,papillae, ormalignant tumor cells.
Benign mucinous cystadenomas compose 80% of mucinousovarian tumors[2] and 20–25% of benign ovarian tumors overall. The peak incidence occurs between 30 and 50 years of age. Benign tumors are bilateral in 5–10% of cases.
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Pancreatic mucinous cystadenoma or mucinous cystadenoma of the pancreas (MCN) are a type of mucinous cysticneoplasm of the pancreas.[3] The cure rate is very high in cases on benigncystic lesions, but the case changes if malignant changes ensue.[4] Benign cystadenomas are the most common cystic tumors of the pancreas accounting for 75% of the cases. On average,mucinous accounts for 40–50% ofcystic tumors, and serouscystadenoma accounts for 30% of it. Mucinous cystadenomas are in thedistal pancreas in about 80% of the cases anddistal pancreatectomy is needed forresection.[4] In 20% of the cases it is in thehead of the pancreas.[3]
Earlier it was believed that MCN occurs exclusively in women who are middle aged. However, occasional occurrence in men have been reported,[3] especially those who are 45 years of age or above.[5]
A rareneoplasm, 95% of cases occur in women, especially at the mean age of 45.[6] Biliarycystadenoma andcystadenocarcinoma constitute less than 5% of intrahepatic cysts originating from thebile duct.[6]
Cystadenomas in liver are often confused withhydatid cyst as their appearance on various imaging techniques is nearly same.[7] Treating cystadenomas ashydatid cyst has resulted in recurrence of the cyst.[7]
Cases of primary retroperitoneal mucinous cystadenoma (PRMC) are extremely rare. However, they are observed more frequently in women, with only four cases having been found in men.[8] Even thoughmucinous cystadenoma are commonovarian tumor, what makes PRMC so rare is theirretroperitoneal location.
PRMC and benign mucinous cystadenoma of the ovary are microscopically similar. Both are multiloculated cystic neoplasms and are lined by a single layer of tallcolumnar cells with a clearbasal nucleus andcytoplasm. Both of them have identicalhistochemical andultrastructural features.[9] Flat to lowcuboidal cells, resemblingmesothelial cells, in the lining interspersed betweencolumnar cells in the same area is the onlyhistological difference between the two tumors.[9]