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Mucicarmine stain

From Wikipedia, the free encyclopedia
Histopathology ofsignet ring cell carcinoma of urinary bladder on mucicarmine stain, coloring the mucin within tumor cells pink/red.

Mucicarmine stain is astaining procedure used for different purposes. Inmicrobiology the stain aids in the identification of a variety ofmicroorganisms based on whether or not thecell wall stains intensely red. Generally this is limited to microorganisms with a cell wall that is composed, at least in part, of apolysaccharide component. One of the organisms that is identified using this staining technique isCryptococcus neoformans.[1]

Another use is in surgical pathology where it can identify mucin. This is helpful, for example, in determining if the cancer is a type that produces mucin.

Example would be to distinguish between high grade Mucoepidermoid Carcinoma of the parotid, which stains positive vs Squamous Cell Carcinoma of the parotid which does not.

References

[edit]
  1. ^Lazcano, O (Jan 1993). "Combined histochemical stains in the differential diagnosis of Cryptococcus neoformans".Modern Pathology.6 (1):80–4.PMID 7678937.
Iron/hemosiderin
Lipids
Carbohydrates
Amyloid
Bacteria
Connective tissue
Other
Tissue stainability


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