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Moxisylyte

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Moxisylyte
Clinical data
Other namesThymoxamine
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 4-[2-(Dimethylamino)ethoxy]-5-isopropyl-2-methylphenyl acetate
CAS Number
PubChemCID
DrugBank
ChemSpider
UNII
KEGG
CompTox Dashboard(EPA)
ECHA InfoCard100.000.186Edit this at Wikidata
Chemical and physical data
FormulaC16H25NO3
Molar mass279.380 g·mol−1
3D model (JSmol)
  • CC1=CC(=C(C=C1OC(=O)C)C(C)C)OCCN(C)C
  • InChI=1S/C16H25NO3/c1-11(2)14-10-15(20-13(4)18)12(3)9-16(14)19-8-7-17(5)6/h9-11H,7-8H2,1-6H3
  • Key:VRYMTAVOXVTQEF-UHFFFAOYSA-N
  (verify)

Moxisylyte, also known asthymoxamine, is a drug used inurology for the treatment oferectile dysfunction.[1] It is anα1-adrenergicantagonist.[2] In the United Kingdom, Moxisylyte is marketed as Opilon (Archimedes Pharma UK Ltd) and is used for the short-term treatment of primaryRaynaud's syndrome. This is a condition where the fingers and toes become discoloured and is triggered by responses to cold, or emotional distress. Opilon tablets help by improving blood circulation to the extremities.[3][4]

References

[edit]
  1. ^British National Formulary 69, Chapter2.6.4, page 142
  2. ^Sakakibara R, Hattori T, Uchiyama T, et al. (March 2000). "Are alpha-blockers involved in lower urinary tract dysfunction in multiple system atrophy? A comparison of prazosin and moxisylyte".J. Auton. Nerv. Syst.79 (2–3):191–5.doi:10.1016/S0165-1838(99)00105-8.PMID 10699651.
  3. ^British National Formulary 70, page 205
  4. ^"Opilon tablets - Patient Information Leaflet (PIL) - (eMC)".www.medicines.org.uk.


Phenylethanolamine derivatives
Alpha blockers
Nicotinic acid and derivatives
Purine derivatives
Ergot alkaloids
Other peripheral vasodilators
Forerectile dysfunction
Prostaglandins (E)
PDE5 inhibitors
Alpha blockers
Dopamine agonists
Melanocortin agonists
Others
Forpremature ejaculation
SSRIs
Oxytocin antagonists
DRA/DRIs
α1
Agonists
Antagonists
α2
Agonists
Antagonists
β
Agonists
Antagonists


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