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Morclofone

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Chemical compound

Pharmaceutical compound

Morclofone
Clinical data

AHFS/Drugs.com	International Drug Names
ATC code	R05DB25 (WHO)
Identifiers
IUPAC name (4-chlorophenyl)-[3,5-dimethoxy-4-(2-morpholin-4-ylethoxy)phenyl]methanone
CAS Number	31848-01-8^Y
PubChemCID	35949
ChemSpider	33063^Y
UNII	VY62TIB872
KEGG	D07395^Y
CompTox Dashboard(EPA)	DTXSID50185710
ECHA InfoCard	100.046.202
Chemical and physical data
Formula	C₂₁H₂₄ClNO₅
Molar mass	405.88 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Clc1ccc(cc1)C(=O)c3cc(OC)c(OCCN2CCOCC2)c(OC)c3
InChI InChI=1S/C21H24ClNO5/c1-25-18-13-16(20(24)15-3-5-17(22)6-4-15)14-19(26-2)21(18)28-12-9-23-7-10-27-11-8-23/h3-6,13-14H,7-12H2,1-2H3^Y Key:KVCJCEKJKGLBOK-UHFFFAOYSA-N^Y
(verify)

Morclofone is acough suppressant.^[1]

References

^Schenker H (April 1983). "[Efficacy of morclofon, a new synthetic antitussive agent, in geriatric patients. Results of a double-blind study]".Therapeutische Umschau. Revue Therapeutique.40 (4):358–61.PMID 6346561.

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Cough and cold preparations (R05)

Cough suppressants

Opium alkaloids, opioids, and derivatives	Acetyldihydrocodeine Benzylmorphine Butorphanol Codeine^# (+guaifenesin) Dextromethorphan Dihydrocodeine Dimemorfan Ethylmorphine Heroin Hydrocodone (+guaifenesin,+homatropine) Hydromorphone Laudanum Levomethadone Levopropoxyphene Methadone Nicocodeine Nicodicodeine Normethadone Noscapine Pholcodine Thebacon
Other	Alloclamide Benproperine Benzonatate Bibenzonium bromide Butamirate Clobutinol Clofedanol Cloperastine Dibunate Dimethoxanate Diphenhydramine Dropropizine Droxypropine Fedrilate Fominoben Gefapixant Glaucine Isoaminile Levodropropizine Meprotixol Moguisteine Morclofone Nepinalone Oxeladin Oxolamine Pentoxyverine Pipazetate Piperidione Prenoxdiazine Tipepidine Zipeprol

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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