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Mittelschmerz

From Wikipedia, the free encyclopedia
Medical term for ovulation pain
Medical condition
Mittelschmerz
Other namesOvulation pain,[1] mid-cycle pain[2]
Approximate location of abdominal pain based on potential causes
SpecialtyGynecology
SymptomsOne sided lowerabdominal pain,spotting[1][2]
Usual onsetMidmenstrual cycle[1]
DurationMinutes to days[1]
CausesRelated toovulation but mechanism unclear[2]
Diagnostic methodAfter ruling out other potential causes[3]
Differential diagnosisAppendicitis,endometriosis,ovarian cyst,ectopic pregnancy,sexually transmitted infections[1][4]
PreventionBirth control pills[1]
TreatmentParacetamol,ibuprofen[1]
PrognosisNone serious[3]
Frequency40% of women[4]

Mittelschmerz (German:[ˈmɪtl̩ʃmɛʁt͡s]) is a term forpain due toovulation. It occurs mid-cycle (between days 7 and 24) and can last minutes to up to several days.[4] The pain affects one side of the lower abdomen and may be dull or sharp in nature.[1][2] Other symptoms may includespotting.[1] Often it occurs monthly and may alternate sides.[4][2]

The underlying mechanism is unclear but may involve irritation due to release of blood and fluid from thefollicle or high blood levels ofluteinizing hormone causing contraction ofsmooth muscle.[2][4][3] Diagnosis involves ruling out other potential causes such asappendicitis,endometriosis,ovarian cysts,ectopic pregnancy, andsexually transmitted infections.[1][4][3]

Treatment may involveparacetamol oribuprofen.[1]Birth control pills may be used for prevention.[1] It is not serious, though may reoccur.[3]Mittelschmerz affects about 20–40% of women.[2][4] The term is from theGerman for "middle pain".[3] Its presence has been used to managefertility.[4]

Signs and symptoms

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Mittelschmerz is characterized by lowerabdominal andpelvic pain that occurs roughly midway through a woman'smenstrual cycle. The pain can appear suddenly and usually subsides within hours, although it may sometimes last two or three days.[5][unreliable medical source?] In some cases it can last up to the following cycle. In some women, the mittelschmerz is localized enough so that they can tell which of their twoovaries provided the egg in a given month.[citation needed] Because ovulation occurs on a random ovary each cycle, the pain may switch sides or stay on the same side from one cycle to another.

Other ovulation symptoms

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Women may notice other physical symptoms associated with their mittelschmerz, during or near ovulation. The most common sign is the appearance of fertile cervical mucus in the days leading up to ovulation. Cervical mucus is one of the primary signs used by various fertility awareness methods. Other symptoms are sometimes calledsecondary fertility signs to distinguish from thethree primary signs.[6][unreliable medical source?]

  • Mid-cycle or ovulatory bleeding is thought to result from the sudden drop in estrogen that occurs just before ovulation. This drop in hormones can trigger withdrawal bleeding in the same way that switching from active to placebobirth control pills does. The rise in hormones that occurs after ovulation prevents such mid-cycle spotting from becoming as heavy or long lasting as a typical menstruation. Spotting is more common in longer cycles.[6][unreliable medical source?]
  • A woman'svulva may swell just prior to ovulation, especially the side on which ovulation will occur.[6][unreliable medical source?]
  • One of the groin lymph nodes (on the side on which ovulation will occur) will swell to about the size of a pea, and may become tender.[6][unreliable medical source?]

Causes

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Mittelschmerz is believed to have a variety of causes:

  • Follicular swelling: The swelling of follicles in the ovaries prior toovulation. While only one or two eggs mature to the point of being released, a number of follicles grow during thefollicular phase of the menstrual cycle (non-dominant follicles atrophy prior to ovulation). Because follicles develop on both sides, this theory explains mittelschmerz that occurs simultaneously on both sides of the abdomen.[6][unreliable medical source?]
  • Ovarian wall rupture: The ovaries have no openings; at ovulation the egg breaks through the ovary's wall. This may make ovulation itself painful for some women.[6][unreliable medical source?]
  • Fallopian tube contraction: After ovulation, thefallopian tubes contract (similar toperistalsis of the esophagus), which may cause pain in some women.[5][unreliable medical source?]
  • Smooth muscle cell contraction: At ovulation, this pain may be related to smooth muscle cell contraction in the ovary as well as in its ligaments. These contractions occur in response to an increased level of prostaglandin F2-alpha, itself mediated by the surge of luteinizing hormone (LH).[7]

Diagnosis

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Diagnosis of mittelschmerz is generally made if a woman is mid-cycle and a pelvic examination shows no abnormalities. If the pain is prolonged and/or severe, other diagnostic procedures such as an abdominalultrasound may be performed to rule out other causes of abdominal pain.

The pain of mittelschmerz is sometimes mistaken forappendicitis and is one of thedifferential diagnoses for appendicitis in women of child-bearing age.

Treatment

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The pain is not harmful and does not signify the presence of disease. No treatment is usually necessary. Pain relievers (analgesics) such as NSAIDs (non-steroidal anti inflammatories) may be needed in cases of prolonged or intense pain.[8]

Hormonal forms of contraception can be taken to prevent ovulation[8]—and therefore ovulatory pain—but otherwise there is no known prevention.

Usefulness

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Women charting with some form offertility awareness may find mittelschmerz to be a helpful secondary sign in detecting ovulation. Because normal sperm life is up to five days, however, mittelschmerz alone does not provide sufficient advance warning to avoid pregnancy. Because other causes of minor abdominal pain are common, mittelschmerz alone also cannot be used to confirm the beginning of the post-ovulatory infertile period.[5][unreliable medical source?][6][unreliable medical source?]

References

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  1. ^abcdefghijkl"Ovulation pain".nhs.uk. 19 October 2017.Archived from the original on 4 July 2023. Retrieved11 January 2024.
  2. ^abcdefgBekaert, Sarah; Bright, Phil (19 April 2018).Women's Health: Medical Masterclass Questions and Explanatory Answers, Pt. 1. 81: CRC Press.ISBN 978-1-4987-9064-2.Archived from the original on 15 January 2024. Retrieved11 January 2024.{{cite book}}: CS1 maint: location (link)
  3. ^abcdefDolan, Brian; Holt, Lynda (4 June 2013).Accident & Emergency: Theory into Practice. Elsevier Health Sciences. p. 452.ISBN 978-0-7020-4315-4.Archived from the original on 15 January 2024. Retrieved11 January 2024.
  4. ^abcdefghBrott, NR; Le, JK (January 2023)."Mittelschmerz".StatPearls.PMID 31747229.Archived from the original on 28 May 2021. Retrieved11 January 2024.
  5. ^abcdKippley, John; Sheila Kippley (1996).The Art of Natural Family Planning (4th ed.). Cincinnati, OH: The Couple to Couple League. pp. 83–84.ISBN 0-926412-13-2.
  6. ^abcdefghWeschler, Toni (2002).Taking Charge of Your Fertility (Revised ed.). New York: HarperCollins. pp. 65–68, 228.ISBN 0-06-093764-5.
  7. ^Michael H. Ross; Wojciech Pawlina (2006).Histology: A Text and Atlas (5th ed.). Hagerstown, MD: Lippincott Williams & Wilkins. p. 788.ISBN 978-0-7817-7221-1.
  8. ^ab"Mittelschmerz".PubMed Health. April 12, 2009. Archived fromthe original on 2011-02-19.

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