Fairley was born in Coleraine to parents Brian and Teresa Fairley, the second eldest of six children. Her father was a popular publican, owner of Fairley's Bar and severaloff-licences, in Northern Ireland duringThe Troubles, but Fairley remembers bothCatholics andProtestants frequenting the pub.[2][3]
Fairley appeared in a number of British television shows, includingThe Bill,Holby City andCasualty. Some of her earlier roles were as Cathy Michaels onITV1'sInspector Morse in the episode titled "The Way Through The Woods" and as Nancy Phelan inLovejoy in the episode 9 of Season 3 titled "Smoke Your Nose".[4]
Fairley has been based inLondon since 1986, and keeps a low public profile. She said in an interview withThe Telegraph in 2015, that she made the decision to separate from her boyfriend of seven years in 2012. Since then, Fairley has had no known partners. Fairley said, in the same interview, that she "missed the gene" for motherhood. She never had the desire to have children like some of her siblings did.[15]
While Fairley has worked on various American projects in the past, she has no love for Hollywood, and theWest End theatres remain her home.[16] She said that while television and movies provide a new challenge by making her "use a different muscle," theatre is where she feels her best work is done, where she started her career, and where she hopes to "end up".[17]