.png) | |
| Names | |
|---|---|
| Preferred IUPAC name Methyl bromoacetate | |
| Other names Bromoacetic acid methyl ester, Methyl α-bromoacetate | |
| Identifiers | |
| |
3D model (JSmol) | |
| ChemSpider |
|
| ECHA InfoCard | 100.002.273 |
| EC Number |
|
| UNII | |
| |
| Properties | |
| C3H5BrO2 | |
| Molar mass | 152.975 g·mol−1 |
| Density | 1.6±0.1 g/cm3[1] |
| Boiling point | 154 °C (309 °F; 427 K) |
| Solubility | Soluble in water |
| Hazards | |
| GHS labelling: | |
   | |
| Warning | |
| H301,H311,H314,H335 | |
| P233,P260,P261,P264,P270,P271,P280,P301,P302,P303,P304,P305,P310,P312,P321,P322,P330,P331,P338,P340,P351,P352,P353,P361,P363,P403,P405,P501 | |
| Flash point | 63 °C (145 °F; 336 K) |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Methyl 2-bromoacetate (methyl bromoactate) is a chemical compound with the molecular formula C3H5BrO2.
Methyl 2-bromoacetate is colorless or straw-colored liquid. The smell is sharp and penetrating. It is soluble in water and also has a higher density than water.[2] It is incompatible with acids, bases, oxidizing agents, and reducing agents.[3]
Methyl bromoacetate is analkylating agent. It has been used to alkylatephenol andamino groups.[4][5] Moreover, it can be used to makevitamins andpharmaceutical drugs. It is commonly used as a reagent in chemical modification of histidine.[2] In addition, methyl bromoacetate also use in synthesize of coumarins and cis-cyclopropane. It reacts with conjugated base and produce alkylated carbene complexes.[3]
Methyl bromoacetate can be toxic by ingestion and inhalation. It can also irritate the skin and eyes as it is a lachrymator.[2]
