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Metamfepramone

From Wikipedia, the free encyclopedia
Stimulant drug
Pharmaceutical compound
Metamfepramone
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • (RS)-2-dimethylamino-1-phenylpropan-1-one
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
ECHA InfoCard100.035.788Edit this at Wikidata
Chemical and physical data
FormulaC11H15NO
Molar mass177.247 g·mol−1
3D model (JSmol)
  • CC(C(=O)C1=CC=CC=C1)N(C)C
  • InChI=1S/C11H15NO/c1-9(12(2)3)11(13)10-7-5-4-6-8-10/h4-9H,1-3H3 ☒N
  • Key:KBHMHROOFHVLBA-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Metamfepramone (INN, also known asdimethylcathinone,dimethylpropion, anddimepropion (BAN)) is astimulantdrug of thephenethylamine, andcathinonechemical classes. Dimethylcathinone was evaluated as anappetite suppressant and for the treatment ofhypotension, but was never widely marketed.[2]

It was used as arecreational drug inIsrael under the namerakefet, but was made illegal in 2006.[3]

Metamfepramone is metabolized to produceN-methylpseudoephedrine andmethcathinone.[4] It has also been found to be about 1.6 times less potent than methcathinone, making it roughly equipotent to cathinone itself.[5]

Legal Status

[edit]

In the United States, metamfepramone (N,N-Dimethyl-cathinone) is considered a Schedule I controlled substance as a positional isomer ofmephedrone.[6]

See also

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References

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  1. ^"Ustawa z dnia 15 kwietnia 2011 r. o zmianie ustawy o przeciwdziałaniu narkomanii ( Dz.U. 2011 nr 105 poz. 614 )". Internetowy System Aktów Prawnych. Retrieved17 June 2011.
  2. ^Soholing WE (February 1982). "[Therapy of the orthostatic syndrome. Studies using dimepropion-HCI]".Fortschritte der Medizin (in German).100 (7):289–293.PMID 7042502.
  3. ^Siegel-Itzkovich J (22 February 2006)."Recreational drug 'rakefet' banned".The Jerusalem Post.
  4. ^Thevis M, Sigmund G, Thomas A, Gougoulidis V, Rodchenkov G, Schänzer W (2009). "Doping control analysis of metamfepramone and two major metabolites using liquid chromatography-tandem mass spectrometry".European Journal of Mass Spectrometry.15 (4):507–515.doi:10.1255/ejms.1010.PMID 19661559.S2CID 41715902.
  5. ^Dal Cason TA, Young R, Glennon RA (December 1997). "Cathinone: an investigation of several N-alkyl and methylenedioxy-substituted analogs".Pharmacology, Biochemistry, and Behavior.58 (4):1109–1116.doi:10.1016/s0091-3057(97)00323-7.PMID 9408221.S2CID 9704972.
  6. ^"Orange Book - List of Controlled Substances and Regulated Chemicals"(PDF).Drug Enforcement Administration.Archived(PDF) from the original on 6 March 2023.
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