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| AHFS/Drugs.com | Consumer Drug Information |
| MedlinePlus | a603026 |
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| ECHA InfoCard | 100.002.313 |
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| Formula | C15H22N2O |
| Molar mass | 246.354 g·mol−1 |
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Mepivacaine/mɛˈpɪvəkeɪn/ is alocal anesthetic[1] of the amide type. Mepivacaine has a reasonably rapid onset (less rapid than that ofprocaine) and medium duration of action (longer than that of procaine)[2][3] and is marketed under varioustrade names includingCarbocaine andPolocaine.
Mepivacaine became available in theUnited States in the 1960s.
Mepivacaine is used in any infiltration andlocal anesthesia.
It is supplied as the hydrochloride salt of theracemate,[4] which consists of R(-)-mepivacaine and S(+)-mepivacaine in equal proportions. These twoenantiomers have markedly different pharmacokinetic properties.[4]
Mepivacaine was originally synthesized in Sweden at the laboratory ofBofors Nobelkrut in 1956.[5]
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