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Megakaryocyte–erythroid progenitor cells (MEPs), among otherblood cells, are generated as a result ofhematopoiesis, which occurs in thebone marrow.Hematopoietic stem cells (HSC) can differentiate into one of two progenitor cells: the common lymphoid progenitor and the common myeloid progenitor. MEPs derive from the common myeloid progenitor lineage.[1] Megakaryocyte–erythroid progenitor cells must commit to becoming either platelet-producing megakaryocytes viamegakaryopoiesis or erythrocyte-producingerythroblasts viaerythropoiesis.[2][3] Most of the blood cells produced in the bone marrow during hematopoiesis come from megakaryocyte–erythroid progenitor cells.[4]
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