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Mefruside

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Mefruside
Clinical data
AHFS/Drugs.comInternational Drug Names
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 4-chloro-N1-methyl-N1-[(2-methyltetrahydrofuran-2-yl)methyl]benzene-1,3-disulfonamide
CAS Number
PubChemCID
ChemSpider
UNII
KEGG
CompTox Dashboard(EPA)
ECHA InfoCard100.027.785Edit this at Wikidata
Chemical and physical data
FormulaC13H19ClN2O5S2
Molar mass382.87 g·mol−1
3D model (JSmol)
  • CC1(CCCO1)CN(C)S(=O)(=O)C2=CC(=C(C=C2)Cl)S(=O)(=O)N
  • InChI=1S/C13H19ClN2O5S2/c1-13(6-3-7-21-13)9-16(2)23(19,20)10-4-5-11(14)12(8-10)22(15,17)18/h4-5,8H,3,6-7,9H2,1-2H3,(H2,15,17,18) ☒N
  • Key:SMNOERSLNYGGOU-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Mefruside (INN) is adiuretic indicated for the treatment of edema and hypertension.[1]

It was developed byBayer A.G. and is sold under the tradenameBaycaron.

References

[edit]
  1. ^Allen HB, Lee DA (1973). "A general practice assessment of mefruside ('Baycaron') in the treatment of oedema and hypertension".Curr Med Res Opin.1 (9):547–53.doi:10.1185/03007997309111720.PMID 4779251.
Sulfonamides
(andetacrynic acid)
CA inhibitors (atPT)
Loop (Na-K-Cl atAL)
Thiazides (Na-Cl atDCT,
Calcium-sparing)
Thiazide-likes (primarilyDCT)
Potassium-sparing (atCD)
ESC blockers
Aldosterone antagonists
Osmotic diuretics (PT,DL)
Vasopressin receptor inhibitors
(DCT andCD)
Other
Combination products


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