Medical textiles are numerousfiber-based materials intended formedical purposes. Medical textile is a sector oftechnical textiles that emphasizesfiber-based products used inhealth care applications such asprevention, care, andhygiene.[1]
The spectrum of applications of medical textiles ranges from simplecottonbandages to advancedtissue engineering.[2] Common examples of products made from medical textiles includedressings,implants,surgical sutures, certain medical devices, healthcare textiles,diapers,menstrual pads,wipes, and barrier fabrics.[3]
Medical textiles include manyfiber types,yarns,fabrics,non-woven materials,woven, braided, as well asknitted fabrics.[4] Physical and chemical alterations of fiber architectures, the use offunctional finishes, and the production of stimuli-sensitive materials are major approaches for developing innovative medical textiles.[3]
Advances intextile manufacturing and medical technologies have made medical healthcare an important industry in textiles.[3] Textiles are used in the production of a variety of medical devices, including replacements for damaged, injured, or non-functioning organs.[5] The manufacture of medical textiles is a growing sector. There are many reasons for its growth, such as new technology in both textiles and medicine; ageing populations; growing populations; changes in lifestyles; and longer life expectancies.[6]: 136 Additionally, theCOVID-19 pandemic generated higher demand for certain medical textile applications [such asPPE,medical gowns andface masks], and there were shortages worldwide.[7][8][9] EvenChina, the world's largest manufacturer of such applications, has struggled to keep up with demand.[10]
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Natural fibers have been used in medical applications since ancient times.[11]: 1, 2 The use ofsplints,bandages, and gauges is very old.[12] An ancient Sanskrit text on medicine and surgery, theSushruta Samhita, categorisesKausheya under the "articles of bandaging."[13] The concept of personal protective equipment (PPE) for medical practitioners dates all the way back to the17th century.Plague doctor costumes were intended to protectplague doctors from the disease during outbreaks of theBubonic Plague in Europe. According to descriptions, the costumes were typically composed of heavy fabric or leather and was waxed.[14][15]
Medical textiles have a critical role in preserving human life. So, e.g., medical textile applications (PPE cover all, N95 masks), were inhigh demand and scarce supply during theCOVID-19 pandemic, resulting in severe shortages.[7][16][8] Considering the shortage, in February 2020, theWorld Health Organization restricted the use of medical essentials such as PPE and masks, etc. tofront-line workers only (PPE includes gowns, aprons, masks, gloves, medical masks, goggles, face shields, and respirators, i.e., N95 or FFP2).[17] PPE protects medical professionals from illness, infections [from virus or bacteria]. The PPE cloth acts as a barrier with the capacity to prevent contaminants from entering the body through respiratory secretions,blood, andbodily fluids.[18]
Masks can protect healthy people from illness by limiting the spread ofrespiratory droplets andaerosols.[19]
There are four different groups of fibers, fabrics and materials used in medical textile products.
| Category | Medical textile products |
|---|---|
| Extracorporeal devices | Artificial organs |
| Implantable materials | Vascular grafts, sutures,artificial joints,and ligaments.[6]: 148 |
| Non-implantable materials | Dressing, bandages, and plaster, etc. |
| Hygiene and healthcare products | Clothing, surgical gowns, bedding, and wipes, etc. |
Different types of fibers and manufacturing systems are utilized for the production of the various medical textile products.[6]
Extracorporeal devices are the artificial organs that remain outside the body while treating a patient. Extracorporeal devices are useful inhemodialysis andcardiac surgery.[20][21]
| Fiber or material types | Extracorporeal devices |
|---|---|
| Viscose (hollow type) | Artificialliver[22] |
| Polyurethane | Artificial heart[23] |
| PP | Lungs[22] |
Implants are medical devices used to replace a missing biological structure, to sustain a damaged biological structure, or to improve an existing biological structure. In contrast to a transplant, which is biomedical tissue that has been transplanted, medical implants are man-made devices such as artificial ligaments and vascular grafts, etc.[6]: 148 [24]
| Fiber or material types | Manufacturing system employed | Implantable materials[6]: 149 |
|---|---|---|
| Polyester, Polytetrafluoroethylene | Weaving, Knitting | Cardiovascular implants such as vascular grafts and heart valves |
| Silicone,Polyethylene,Polyoxymethylene | Orthopedic implants such as artificial bones and joints | |
| Polylactic acid,Polyglycolide,Collagen | Monofilament or braided | Biodegradablesurgical sutures |
| Steel, Polytetrafluoroethylene, Polyester, Nylon | Monofilament or braided | Non-biodegradable surgical sutures |
| Soft tissue implants such as the following: | ||
|
| |
| Polyester, Carbon | Braiding | Ligaments |
| Low-density polyethylene | Nonwoven | Cartilage |
Non-implantable materials are used externally and may or may not contact skin. For example, bandages, plaster, orthopedic belts, pressure garments, etc.[25][6]: 147, 148
| Fiber or material types | Manufacturing system employed | Non-implantable materials[22][6]: 141 to 148 |
|---|---|---|
| Nylon, Cotton, and Spandex | Knitting and Weaving | Compression bandages |
| Cotton, Viscose, Polyamide, and Spandex | Weaving, Knitting, and Nonwoven | Ordinary bandages which are elastic or non-elastic |
| Cotton, Viscose, Polyurethane foam, Polypropylene, and Polyester | Weaving, Nonwoven | Orthopedic bandages |
| Cotton, Viscose | Knitting, Weaving | Gauges |
| Cotton, Viscose, Plastic films, Glass, Polypropylene, and Polyester | Knitting, Weaving, and Nonwoven | Plasters |
| Cotton, Viscose | Nonwoven | Absorbent pads in wound care |
| Cotton, Chitosan | Weaving | Antimicrobial dressings[26][27][2]: 145–151 |
The term "hygiene and healthcare products" refers to a variety of materials used to maintain the hygiene, safety, and care of medical professionals and patients.[6]: 157 Surgical drapes, gowns, uniforms, clothing, caps, wipes, masks, and hospital bed linens are all included in this category[28]
| Fiber types | Manufacturing system employed | Hygiene and healthcare products[28] |
|---|---|---|
| Polyester, Polypropylene | Nonwoven | Protective clothes |
| Cotton, Polyester | Weaving | Uniforms |
| Polyester, Polypropylene, Cotton | Weaving, Nonwoven | Medical gowns |
| Polyester, Viscose, Glass | Nonwoven | Masks |
| Cotton | Weaving | Sheets and Pillow covers |
| Polyester, Cotton | Weaving, Knitting | Blankets |
| Polyester,Superabsorbent polymer | Nonwoven | Diapers[28] |
Human textiles refer to textiles that utilize human materials, including bioengineered yarns made from human cells, for tissue regeneration. Textiles manufactured from human tissue-based 'yarn' can be intricately woven, knitted, or braided and have the potential to contribute to various applications, ranging from simple biocompatible sutures to complex woven tissues for surgical repairs, thereby aiding in the healing process of injuries. Human textiles offer a potential solution to mitigate the drawbacks associated with foreign agents that may induce adverse side effects.[29]
The Cell-AssembledExtracellular matrix (CAM) is both biologically sound and resilient, allowing for large-scale production suitable for clinical applications utilizing regular, adult humanfibroblasts.[29]
In the medical field, most permanent synthetic biomaterials are considered foreign by the innate immune system. This can lead to aforeign body reaction when implanted.[29][30]
Products made from medical textiles are specially engineered textile-based products used in medical applications. These products are used for prevention, care, and hygiene purposes.A combination of properties are considered while selecting the materials, which largely depends upon the particular use. The materials used in medical textile products must have the following properties: strength,softness,biocompatibility,elasticity, flexibility,nontoxicity,noncarcinogenic,non-allergenic, andair andwater permeability.[6]: 136, 137
Biotextiles are constructions made of textile fibers that are employed in both implantable and non-implant applications. Their performance is assessed according to their biofunctionality, biocompatibility, and biostability. For example, biostability in the presence ofbody fluids andcells.[31]
Medical devices are commonly made in whole or part from fibers. A medical device is defined as any device intended for medical purposes. It could be a machine, a reagent for use in the lab, software, an appliance, an instrument, or an implant.[32] For medical use, fiber selection is based on certain criteria of intended use. Primarily, fibers are chosen on the basis of their biodegradability or non-biodegradability. Other than biodegradability, strength, elasticity, and absorbency are also considered.
Natural fibers such as cotton, silk, and viscose (a regenerated cellulosic fiber) are used in hygiene and healthcare products, as well as non-implantable materials. Polyester, nylon, polypropylene, glass, and carbon are all examples of synthetic fibers used in Medical textiles.[6]: 136 Fibers absorbed within three months by ourbiological system are considered biodegradable, and fibers that require more than six months to absorb are called non-biodegradable. These fibers are categorized as below:[6]: 136, 137
| Biodegradable | Non-biodegradable | |
|---|---|---|
| Fibers | Cotton | Polyester |
| Viscose | Polypropylene | |
| Polyamide | Polytetrafluoroethylene | |
| Polyurethane |
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Polylactic acid, also called PLA, is a biodegradable, biosorbable or bioabsorbablepolymer used in producing many type of implants such asnaturally dissolving stents.[6]: 140 Polyglycolide or polyglycolic acid, also called PGA, is a biodegradable and thermoplastic polymer.[33] PGA suture is categorized as an absorbable synthetic braided multifilament.[34]
| Biodegradable | Non-biodegradable | |
|---|---|---|
| Polymers | Alginate | |
| Collagen | ||
| Chitin | ||
| Chitosan |
The term "medical textile" refers to various products made of textile materials (fiber, yarn, or fabric) that are used in the medical environment. Although both natural andsynthetic fibers are used in medical textiles, properties such as modulus of elasticity, tensile strength, and hardness are mostly fixed factors in natural fibers, and have proven to be more manageable in synthetic fibers.[11]: 2 Recent fiber developments have a significant impact on four primary areas of medical textiles: hygiene products, implants, non-implantable medical textiles, and extracorporeal medical textiles.[11]
Medical textiles serve as a bridge between biological sciences and engineering.[35]: xxxiii The advancement ofmaterials science and related research has resulted in the introduction of newfiber materials and manufacturing processes for the medical sector. As a result of new technologies such as3D printing,electrospinning andmelt blowing technology in textiles, medical professions now have access to a diverse choice of textile materials with varying designs and qualities.[3]
Melt blowing is a well-established technology for fabricating micro- and nanofibers, in which a polymer melt is extruded via small nozzles surrounded by a high-speed blowing gas. Melt-blown microfibers typically have a fiber diameter of 2–4 μm, but can be as small as 0.3–0.6 μm or as large as 15–20 μm. Melt blowing technology helps in producing filtering products such as N95 masks, and female hygiene products.[36][37]
Medical textiles use tubular fabrics with carefully chosen materials that are biocompatible, nonallergic, and nontoxic. For example, Dyneema, PTFE,Polyester, and Teflon are used for implants. The material type varies depending on the implant area; for example,Polytetrafluoroethylene is preferred forstent implants due to itsnon-stick properties, whilepolyolefin is used for mesh implants.[38][39]
Vectran, a manufactured fiber fromliquid-crystal polymer, is used in producing medical devices, for example, implants and certain surgical devices.[40]
Intelligent textiles can be used fordisease management as well asremote monitoring.[41]: 373 Intelligent textiles can monitorheart rate andblood pressure, which are critical components ofmedical diagnosis, and controlling them considerably reduces the incidence of serious health disorders. Movement patterns andelectroencephalograms are used to diagnoseneurological illnesses and to guide treatment decisions.[41]: 375
Phase-change materials are helpful in medical textiles because they can be utilized to reheathypothermia patients softly and precisely. Additionally, the PCM can be incorporated therapeutically into elastic wraps or orthopedic joint supports. It makes it easy to provide heat or cold therapy to joints or muscles while wearing a bandage.[41]: 54, 55
Materials withshape-memory polymers that have the capabilities of temperature adaptive moisture management can improve the thermo-physiological comfort of patients.[42]
Nonwoven fabrics with two or more fibers layers are widely used in a variety of applications, including tissue engineering scaffolds, wipes, wound dressings, and barrier materials.[43]
Microfluidic spinning technology is used for fabricating many type of fibers. Due to its ease of manipulation, high efficiency, controllability, and environmentally friendly chemical process, microfluidic systems have been identified as an appropriate microreactor platform for the production of anisotropic fibers.[44][45]
Medical textiles cover a vast area of application that includeswound care, disease management,preventive clothing, bandages, hygiene (hospital linen), etc. Medical textiles are useful infirst aid, treating a wound or keeping a wound or illness in the right condition during medical treatment, they also helps in protecting thehealthcare workers fromInfection andinfectious diseases.[3]
Knitting, weaving, braiding, crocheting, composite materials, and non-woven technologies are all different fabric manufacturing systems used in contemporary wound care.[46] Research subjects in medical textiles include materials and products with significantly superior attributes produced using advanced technology and novel methodologies. New medical textiles are an emerging field with significant growth in wound treatment products. These are all important characteristics of wound care fibers and dressings. They are non-toxic, non-allergic, absorbent, hemostatic, biocompatible, breathable, and non-toxic. They also have good mechanical properties. Chitosan, Alginate, Collagen, branan ferulate, and carbon fiber-based goods offer numerous advantages over conventional materials. Materials used in wound care also include foams, hydrogels, films, hydrocolloids, and matrix (tissue engineering).[46]
Textile technologies are now being considered forbiofabrication. The physical and chemical properties of fibers, the size of the pores, and the strength of the fabric all play a role in how textile technologies can be used in tissue engineering.[47] Fibrous structures can be made and shaped with textile technology to meet the needs of a wide range oftissue engineering applications. Tissue engineering is the process of putting together scaffolds, cells, and biologically active molecules to make functional tissues.[48][49]
Hydrogel fibers are used to construct scaffolds for the development of cells and the release of drugs.[49][52]
Chitosan may function as an inhibitor of bacterial and fungal development.[26] In 2003, the United StatesFood and Drug Administration approved chitosan-based wound dressings for medical use.[27]Combat medics use Hemcon dressings, which is a dressing with Chitosan, to treat wounds because it stops theblood flow with itshemostasis properties.[26][27] Chitosan hemostatic agents are salts formed when chitosan is combined with an organic acid (lactic acid, orSuccinic acid). The hemostatic agent operates by interacting with the erythrocytes' (negatively charged) cell membrane and the protonated chitosan (positively charged), resulting in platelet involvement and fast thrombus formation.[53] When the bandage comes into contact with blood, it becomes sticky, creating an adhesive-like effect that seals the cut.[54]
Materials in surgical sutures are textile based products. Suture material is frequently subdivided into absorbable thread and non-absorbable thread, and then into synthetic fibers and natural fibers. Whether a suture material is monofilament or polyfilament is an additional critical distinction.[55]
A bandage is a piece of fabric used to cover, dress, and bind wounds. Bandages are typically manufactured from various textile materials. The dressing or splint is held in place using a bandage. Bandages are also used for medical purposes (strengthening and compressing) to support and restrict specific body parts.[56][6]: 142
Compression bandages are used to apply pressure while directed pressure is used to treatlymphatic disease orvenous disease,[2]: 111, 241 such as in the treatment ofdeep vein thrombosis.[6]: 142 The most common classifications for compression bandages are inelastic and elastic.[57]
Antimicrobial textiles are the textile materials (fibers, yarns and fabrics) treated with antimicrobial agents, they are used in hygiene care.Antimicrobial treated textiles either kill thebacteria or inhibit the growth ofmicroorganisms. The exemplary products are wipes, gowns,Odorless clothes, etc.[58] Antimicrobialscrubs are hospital garments treated with anti bacterial chemicals. Their primary objective is to prevent the spread of hazardous microorganisms between healthcare staff and between patients. The applied chemicals work differently, for example, chemical binds to the microbe's DNA, effectively rendering reproduction impossible. Some antimicrobial chemicals dissolve the protein necessary for their growth, there are antimicrobials which attack specific bacteria such asStaphylococcus,Salmonella, andEscherichia coli.[59]
Antiviral textiles are an extension of antimicrobial surfaces. These surfaces, which have antiviral capabilities, may be able to inactivate lipid-coated viruses.[60]Polyhexamethylene biguanide (PHMB) treated CVC fabric (fabric with chief value cotton) kills 94% of thecoronavirus in two hours. Henceforth, it is suitable for PPE for health workers.[61] Chitosan, a natural polymer that is biocompatible, non-allergenic, biodegradable, and non-toxic, was also looked at for its antiviral properties. The chitosan-based compound also shows efficacy againstsevere acute respiratory syndrome coronavirus 2 and cotton fabrics treated withcopper along with chitosan andcitric acid. The treated material sustains the antiviral properties five to ten home laundry washes.[62]
Medical gowns are a kind of PPE for medical professionals. Gowns are a component of a comprehensive infection-control approach. They protect the wearer from getting sick or getting infected if they come into contact with liquids or solids that could be contagious or harmful. Operating room gowns, surgical gowns, isolation gowns, nonsurgical gowns, and procedural gowns are all terms used to describe different gowns used in health care settings. The names of products are not standardized. The specifications of the products are important. ANSI/AAMI PB70 specifies a classification system for protective gear [including isolation gowns and surgical gowns] used in healthcare facilities in the United States based on its liquid barrier performance. Quality requirements for various gowns include seam strength, lint generation, tear resistance, evaporative resistance, and breathability.ASTM International [ASTM F2407] guidelines include a list of them which are approved by FDA.[63]
These gowns are either impermeable or made of a densely woven, water-resistant fabric.[64] 510(K) is a premarket submission made to the Food and Drug Administration in order to demonstrate that the device to be sold is safe and effective. Surgical and surgical isolation gowns are regulated by the FDA as Class II medical devices that require a 510(k). Non-surgical gowns are class I medical devices that do not need a 510(k) clearance.[65]
The different levels are categorized as follows:[63]
| Level | Risk | Exposure | Product usable as/at | Protection levels | Tests |
|---|---|---|---|---|---|
| One | Minimum | Standard isolation, Basic care | Visitor gown | Allows small amount of fluid penetration. Slight barrier to fluids. | Only one test of water impacting the gown material's surface is conducted to determine barrier protection. |
| Two | Low | Surgical suturing, and during blood draw | Pathology lab,Intensive care unit | Protection from fluids for longer period than level one gowns. | Two tests
|
| Three | Moderate | Intravenous therapy, and to drawarterial blood | InTrauma cases, or atEmergency | Protection from fluids for longer period than level two gowns. | Two tests
|
| Four | High | Surgery, and wherepathogen transmission suspected | Operating theater | Protection against fluids and virus for one hour. | Three tests
|
Some more examples of medical textile applications in the medical environment include the following:
![A surgical face mask, meant for single use.[66] It is a type of the face masks often used to prevent the spread of Coronavirus. They are used in countries with coronavirus disease (COVID-19) outbreaks and are worn in hospitals as well as in public. They are not designed to protect the wearer from inhaling airborne bacteria or virus particles and are less effective than respirators, such as N95 or FFP masks.[69]](/mt/?noimg=&dark=on&url=http%3a%2f%2fen.wikipedia.org%2fwiki%2fFile%3aSurgical_face_mask.jpg)
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