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Mebroqualone

From Wikipedia, the free encyclopedia
Chemical compound
Pharmaceutical compound
Mebroqualone
Clinical data
ATC code
  • none
Legal status
Legal status
Identifiers
  • 3-(2-bromophenyl)-2-methylquinazolin-4(3H)-one
CAS Number
PubChemCID
ChemSpider
UNII
CompTox Dashboard(EPA)
Chemical and physical data
FormulaC15H11BrN2O
Molar mass315.170 g·mol−1
3D model (JSmol)
  • BrC1=C(N2C(C3=CC=CC=C3N=C2C)=O)C=CC=C1
  • InChI=1S/C15H11BrN2O/c1-10-17-13-8-4-2-6-11(13)15(19)18(10)14-9-5-3-7-12(14)16/h2-9H,1H3 checkY
  • Key:NBUSAPJNASSKBP-UHFFFAOYSA-N checkY
  (verify)

Mebroqualone (MBQ) is aquinazolinone-classGABAergic and is an analogue ofmecloqualone that has similarsedative andhypnotic properties to its parent compound, resulting from its agonist activity at the β subtype of theGABAa receptor. It was originally synthesized in the 1960s[1] Mebroqualone differs from mecloqualone by having a bromine atom instead of a chlorine on the 3-phenyl ring. It was made illegal in Germany in 1998 but little other information is available. It would appear that this compound was sold on the black market in Germany as a designer druganalogue of mecloqualone.[2]

See also

[edit]

References

[edit]
  1. ^Jackman GB, Petrow V, Stephenson O (September 1960). "Some 2, 3-disubstituted 3H-4-quinazolones and 3H-4-thioquinazolones".The Journal of Pharmacy and Pharmacology.12:529–38.doi:10.1111/j.2042-7158.1960.tb12705.x.PMID 14406263.S2CID 31254238.
  2. ^"Zwölfte Verordnung zur Änderung betäubungsmittelrechtlicher Vorschriften".Bundesgesetzblatt.I (68): 3126. 7 October 1998.
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