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Mebhydrolin

From Wikipedia, the free encyclopedia
Chemical compound

Pharmaceutical compound
Mebhydrolin
Clinical data
Other names9-Benzyl-2-methyl-2,3,4,9-tetrahydro-1H-gamma-carboline, Incidal, Omeril, Diazolin, Fabahistin, mebhydrolin napadisylate, mebhydroline 1,5-naphthalenedisulfonate[1]
AHFS/Drugs.comInternational Drug Names
Pregnancy
category
  • Not established[2]
Routes of
administration
Oral[2]
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
  • 5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole
CAS Number
  • 524-81-2 checkY
    6153-33-9 (1,5-naphthalenedisulfonate salt)[3]
PubChemCID
ChemSpider
UNII
KEGG
CompTox Dashboard(EPA)
ECHA InfoCard100.007.606Edit this at Wikidata
Chemical and physical data
FormulaC19H20N2[4]
Molar mass276.383 g·mol−1
3D model (JSmol)
  • CN3Cc4c1ccccc1n(Cc2ccccc2)c4CC3
  • InChI=1S/C19H20N2/c1-20-12-11-19-17(14-20)16-9-5-6-10-18(16)21(19)13-15-7-3-2-4-8-15/h2-10H,11-14H2,1H3 checkY
  • Key:FQQIIPAOSKSOJM-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Mebhydrolin (INN) ormebhydroline is anantihistamine. It is not available in the United States, but it is in various other countries under the brand namesBexidal(BD) andDiazolin(RU). It is used for symptomatic relief of allergic symptoms caused by histamine release, including nasal allergies and allergic dermatosis.

Mebhydrolin has been shown to magnify the performance-deficit effects of alcohol.[5]

References

[edit]
  1. ^"Mebhydroline".National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Retrieved2007-03-02.
  2. ^ab"FABAHISTIN 50 mg (Tablets)".South African Electronic Package Inserts. September 1970. Archived fromthe original on October 17, 2006. Retrieved2007-03-02.
  3. ^"Diazoline".National Library of Medicine - Medical Subject Headings. US National Institutes of Health, National Library of Medicine. Archived fromthe original on January 19, 2016. Retrieved2007-03-02.
  4. ^"Mebhydrolin chemical information".PubChem. Retrieved2007-03-02.
  5. ^Franks HM, Lawrie M, Schabinsky VV, Starmer GA, Teo RK (October 1981). "Interaction between ethanol and antihistamines: 3. mebhydrolin".Med. J. Aust.2 (9):477–9.doi:10.5694/j.1326-5377.1981.tb112944.x.PMID 6119605.S2CID 11034501.
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