Steenburgen was born February 8, 1953, inNewport, Arkansas, to Nellie Mae (née Wall),[2] a school-board secretary, and Maurice Hoffman Steenburgen, a freight-train conductor who worked for theMissouri Pacific Railroad.[3][4][1][5] She has a sister, Nancy Kelly (née Steenburgen), a teacher.[6] In 1971, she enrolled atHendrix College to study drama.[1] She subsequently traveled toDallas at the suggestion of her drama teacher where she successfully auditioned for New York City'sNeighborhood Playhouse School of the Theatre.[1]
Steenburgen moved toManhattan in 1972 after the Neighborhood Playhouse offered her an opportunity to study acting. She worked as a server atThe Magic Pan and forDoubleday while studying underWilliam Esper.[6]
Steenburgen's break came when she was discovered byJack Nicholson in the reception room ofParamount Pictures's New York office and was cast as the female lead in his second directorial work, the Western comedyGoin' South (1978).[6] Steenburgen had a leading role in the filmTime After Time (1979), for which she won theSaturn Award for Best Actress. She played a modern woman who falls in love with authorH. G. Wells, played byMalcolm McDowell, whom she married the following year.
In television, Steenburgen appeared as Kate Montgomery inInk (1996) and co-starred as Mary Gulliver inGulliver's Travels (1996). She has a recurring role as herself inCurb Your Enthusiasm. Steenburgen co-starred as Helen Girardi, the mother ofAmber Tamblyn's title character inJoan of Arcadia. In 2011, she had a recurring role as Josephine in theHBO sitcomBored to Death. Steenburgen starred as Anastasia Lee in the 2011FX pilotOutlaw Country,[7] but it was passed by the network.[8] She appeared in the dark sitcomWilfred from 2011 through 2013 as Catherine Newman, the title character's eccentric and mentally ill mother. Steenburgen had a recurring role as Diana Jessup on theNBC sitcom30 Rock from 2012 to 2013.
In 2014, she began a recurring role as former Dixie Mafia boss Katherine Hale in the fifth and sixth seasons ofJustified.
From 2015 to 2018, she starred as Gail Klosterman on the comedy seriesThe Last Man on Earth.
From 2020 to 2021, she played the role of Maggie Clarke in the NBC musical comedy-drama seriesZoey's Extraordinary Playlist for two seasons. She reprised the role forThe Roku Channel television filmZoey's Extraordinary Christmas.
In 2007, Steenburgen underwent minor surgery on her arm, which required ageneral anaesthetic; shortly thereafter, she began experiencing "music (...) playing in her head day and night". She subsequently took music lessons so that she could write down what she was hearing, and by 2013 had almost 50 songwriting credits.[9] She has collaborated with musicians from Nashville and was also signed toUniversal Music Group as a songwriter.[10] She performs one of her own songs inLast Vegas.[11]
In 1978, Steenburgen met and began dating actorMalcolm McDowell while they were co-starring inTime After Time.[14] They married and had two children together, including sonCharlie McDowell. They divorced in 1990.[15] On October 7, 1995, Steenburgen married actorTed Danson, whom she had met on the set of the filmPontiac Moon, and became the stepmother to Danson's two daughters from his previous marriage.[16][17]
Steenburgen resides in the Los Angeles area with her family.[18] An alumna ofHendrix College, she received an honorary doctorate from the institution in 1989.[19] In 2006, Steenburgen received an honorary Doctor of Humane Letters degree fromLyon College inBatesville, Arkansas.[20] In September 2005, she and Danson gave a guest lecture for students at theClinton School of Public Service, where they discussed their roles in public service as well as the foundations and causes in which they are involved.[21]
Since 2014, Steenburgen's son Charlie McDowell has had a running joke at her expense, claiming on numerous occasions onsocial media that his mother is actressAndie MacDowell.[24]