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| ECHA InfoCard | 100.038.775 |
| Chemical and physical data | |
| Formula | C14H10MgO6 |
| Molar mass | 298.533 g·mol−1 |
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Magnesium salicylate is a commonanalgesic[1] andnonsteroidal anti-inflammatory drug (NSAID)[2] used to treat mild to moderatemusculoskeletal pain[3] such asin tendons andmuscles.[citation needed] It is also used to treatjoint pain likearthritis,[2][3] generalback pain,[4] andheadaches.[citation needed]
It is found in a variety ofover-the-counter (OTC) medications, most notably the brandDoan's Pills, as ananti-inflammatory, primarily for back-pain relief. Magnesium salicylate can be an effective OTC alternative to prescription NSAIDs, with both anti-inflammatory and pain-relieving effects.[1]
While magnesium salicylate is sold as an alternative for pain relief, it is still a nonsteroidal anti-inflammatory drug and, like others in this class, can cause stomach ulcers,[2] without any proven superiority to other over-the-counter pain relievers.
Novartis, the company that produces Doan's Pills,[4] has claimed that the product is superior in providing back pain relief. In June 1996, the USFederal Trade Commission (FTC) charged the company with violating federal law with its unsubstantiated claim.[5][4] In March 1998, the court ruled in favor of the FTC, but there was no stipulation about how the company should or would have to amend its advertising and packaging. Thus, Doan's was able to continue marketing as a "superior treatment for back pain".[5] In May 1999, the FTC released a statement summarizing the proceedings and announced the commission's decision after a 4–0 vote imposing a penalty on Doan's and its marketer, Novartis, to "run ads to correct misbeliefs resulting from their unsubstantiated claim that Doan's Pills are superior to other over-the-counter analgesics for treating back pain" and to modify packaging to include the statement "Although Doan's is an effective pain reliever, there is no evidence that Doan's is more effective than other pain relievers for back pain."[4] The ads were required to run for a period of one year.[5]
| pyrazolones / pyrazolidines | |
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| salicylates | |
| acetic acid derivatives and related substances | |
| oxicams | |
| propionic acid derivatives (profens) |
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| n-arylanthranilic acids (fenamates) | |
| COX-2 inhibitors (coxibs) | |
| other | |
| NSAID combinations | |
Key:underline indicates initially developed first-in-class compound of specific group;#WHO-Essential Medicines;†withdrawn drugs;‡veterinary use. | |
