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| Other names | 5,6-Methylenedioxy-N-methyl-2-aminoindane; MDMAI |
| Drug class | Serotonin releasing agent;Entactogen |
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| Formula | C11H13NO2 |
| Molar mass | 191.230 g·mol−1 |
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MDMAI, also known as5,6-methylenedioxy-N-methyl-2-aminoindane, is adrug of the2-aminoindane family developed in the 1990s by a team led byDavid E. Nichols atPurdue University.[1][2] It acts as a non-neurotoxicserotonin releasing agent (SRA) in animals and is a putativeentactogen in humans.[1][2]
MDMAI was first described in thescientific literature byDavid E. Nichols and colleagues in 1990.[1][2]
MDMAI can be thought of as acyclizedanalogue ofMDMA where the α-methyl group of the alkylamino side chain has been joined back round to the 6-position of the aromatic ring to form anindane ring system. This changes the core structure of the molecule fromphenethylamine to2-aminoindane, and causes the pharmacological properties of the two compounds to be substantially different.[2]