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| Names | |
|---|---|
| Other names Trilithium citrate trilithium 2-hydroxypropane-1,2,3-tricarboxylate | |
| Identifiers | |
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3D model (JSmol) | |
| ChEBI | |
| ChEMBL | |
| ChemSpider |
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| DrugBank | |
| ECHA InfoCard | 100.011.860 |
| EC Number |
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| RTECS number |
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| UNII | |
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| Properties | |
| Li3C6H5O7 | |
| Molar mass | 209.923 g mol−1 |
| Appearance | Odorless white powder |
| Melting point | decomposes at 105 °C (221 °F; 378 K) |
| Hazards | |
| GHS labelling: | |
 | |
| Warning | |
| H302,H319 | |
| P305+P351+P338 | |
| Flash point | N/A |
Except where otherwise noted, data are given for materials in theirstandard state (at 25 °C [77 °F], 100 kPa). | |
Lithium citrate (Li3C6H5O7) is alithium salt ofcitric acid that is used as amood stabilizer in psychiatric treatment ofmanic states andbipolar disorder.[1][2][3][4] There is extensivepharmacology of lithium, the active component of this salt.
Lithium citrate was one of the lithium salts used to add lithium to drinks and water (lithia water) in the late 19th century and the early 20th century, when there was a general health craze for lithium with it believed to be a cure-all.[5] Thesoft drink7Up was at one point named "7Up Lithiated Lemon Soda" when it was formulated in 1929 because it claimed to contain lithium citrate. The beverage was apatent medicine marketed as a cure forhangover. In 1936 the federal government forced the manufacturer to remove a number of health claims, and because "lithium was not an actual ingredient", the name was changed to just "7 Up" in 1937.[6]: §2 Many sources repeat an incorrect version of the story where the name is "Bib-Label Lithiated Lemon-Lime Soda" and the removal happened in 1948 due to aFood and Drug Administration ban.[7][8]
Lithium citrate is used as a mood stabilizer and is used to treatmania,hypomania,depression andbipolar disorder.[9] It can be administered orally in the form of a syrup.[9]
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