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List of Schedule IV controlled substances (U.S.)

From Wikipedia, the free encyclopedia

This is thelist of Schedule IV controlled substances in the United States as defined by theControlled Substances Act.[1] The following findings are required for substances to be placed in this schedule:[2]

  1. The drug or other substance has a low potential for abuse relative to the drugs or other substances inschedule III.
  2. The drug or other substance has a currently accepted medical use in treatment in the United States.
  3. Abuse of the drug or other substance may lead to limited physical dependence or psychological dependence relative to the drugs or other substances in schedule III.

The complete list of Schedule IV substances is as follows. TheAdministrative Controlled Substances Code Number andFederal Register citation for each substance is included.

Narcotics

[edit]
ACSCNDrug
9167Not more than 1 milligram ofdifenoxin and not less than 25 micrograms ofatropine sulfate per dosage unit.[3]
9278Dextropropoxyphene[4]
9752Tramadol[5]

Depressants

[edit]
ACSCNDrug
2731Alfaxalone[6]
2882Alprazolam[7]
2145Barbital[8][note 1]
2400Brexanolone[9]
2748Bromazepam[10]
2749Camazepam[10]
8192Carisoprodol[11]
2460Chloral betaine[8][note 1]
2465Chloral hydrate[8][note 1]
2744Chlordiazepoxide[12]
2751Clobazam[10]
2737Clonazepam[12]
2768Clorazepate[12]
2752Clotiazepam[10]
2753Cloxazolam[10]
2410Daridorexant[13]
2754Delorazepam[10]
2765Diazepam[12]
2467Dichloraphenazone[14]
2756Estazolam[10]
2540Ethchlorvynol[8][note 1]
2545Ethinamate[8][note 1]
2758Ethyl loflazepate[10]
2759Fludiazepam[10]
2763Flunitrazepam†[10]
2767Flurazepam[12]
2138Fospropofol[15]
2762Halazepam[16]
2771Haloxazolam[10]
2772Ketazolam[10]
2245Lemborexant[17]
2773Loprazolam[10]
2885Lorazepam[18]
2774Lormetazepam[10]
2800Mebutamate[19]
2836Medazepam[10]
2820Meprobamate[8][note 1]
2264Methohexital[8][note 1]
2250Methylphenobarbital (mephobarbital)[8][note 1]
2884Midazolam[20]
2837Nimetazepam[10]
2834Nitrazepam[10]
2838Nordiazepam[10]
2835Oxazepam[12]
2839Oxazolam[10]
2585Paraldehyde[8][note 1]
2591Petrichloral[8][note 1]
2285Phenobarbital[8][note 1]
2883Pinazepam[10]
2764Prazepam[21]
2881Quazepam[20]
2846Remimazolam[22]
2223Suvorexant[23]
2925Temazepam†[24]
2886Tetrazepam[10]
2887Triazolam[25]
2781Zaleplon[26]
2783Zolpidem[27]
2784Zopiclone[28]
2420Zuranolone[29]

†Flunitrazepam has not been approved by the Food and Drug Administration for medical use, and is considered to be an illegal drug.

†Temazepam may require a specially coded prescription in certain States.

Lorcaserin

[edit]
ACSCNDrug
1625Lorcaserin[30]

Stimulants

[edit]
ACSCNDrug
1230Cathine[31]
1610Diethylpropion[32]
1760Fencamfamin[31]
1575Fenproporex[31]
1605Mazindol[33]
1580Mefenorex[31]
1680Modafinil and enantiopurearmodafinil[34]
1530Pemoline[35]
1640Phentermine[32]
1750Pipradrol[36]
1729Serdexmethylphenidate[37]
1675Sibutramine[38]
1650Solriamfetol[39]
1635SPA / (-)-1-dimethylamino- 1,2-diphenylethane[36]

Others

[edit]
ACSCNDrug
9709Pentazocine[40]
9720Butorphanol[41]
9725Eluxadoline[42]

See also

[edit]

Notes

[edit]
  1. ^abcdefghijkThis substance was expressly scheduled by theControlled Substances Act on October 27, 1970. The 1974Federal Register ruling (by Administrator John R. Bartels, Jr.) merely organized its listing in theCode of Federal Regulations.

References

[edit]
  1. ^"21 CFR 1308.14 (Schedule IV)".Code of Federal Regulations. RetrievedSeptember 9, 2023.
  2. ^21 U.S.C. § 812(b)(4) retrieved October 2, 2007
  3. ^Bensinger, Peter (August 28, 1978)."Placement of Preparations Containing Difenoxin in Combination With Atropine Sulfate Into Schedules IV and V"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  4. ^Bensinger, Peter (July 24, 1980)."Classification of Dextropropoxyphene as a Narcotic Drug in Schedule IV of the Controlled Substances Act"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  5. ^Harrigan, Thomas (July 2, 2014)."Schedules of Controlled Substances: Placement of Tramadol Into Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedJanuary 16, 2023.
  6. ^Leonhart, Michele (February 27, 2014)."Schedules of Controlled Substances: Placement of Alfaxalone into Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedJanuary 16, 2023.
  7. ^Mullen, Jr., Francis M. (November 12, 1981)."Schedules of Controlled Substsnces; Placement of Alprazolam in Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  8. ^abcdefghijkBartels Jr., John R. (June 20, 1974)."PART 1308— SCHEDULES OF CONTROLLED SUBSTANCES: Annual Publication"(PDF).Government Publishing Office.Drug Enforcement Administration. Archived fromthe original(PDF) on September 6, 2023. RetrievedSeptember 6, 2023.
  9. ^Dhillon, Uttam (January 24, 2020)."Schedules of Controlled Substances: Placement of Brexanolone in Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedSeptember 6, 2023.
  10. ^abcdefghijklmnopqrstuMullen, Jr., Francis M. (October 5, 1984)."Schedules of Controlled Substances; Temporary Placement of Bromazepam, Camazepam, Clobazam, Clotiazepam, Cloxazolam, Delorazepam, Estazolam, Ethyl Loflazepate, Fludiazepam, Flunitrazepam, Haloxazolam, Ketazolam, Loprazolam, Lormetazepam, Medazepam, Nimetazepam, Nitrazepam, Nordiazepam, Oxazolam, Pinazepam, and Tetrazepam Into Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  11. ^Leonhart, Michele (December 12, 2011)."Schedules of Controlled Substances: Placement of Carisoprodol Into Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedJanuary 16, 2023.
  12. ^abcdefBartels, Jr., John R. (May 28, 1975)."Schedules of Controlled Substances; Placement of Chlordiazepoxide, Diazepam, Oxazepam, Chlorazepate, Flurazepam, and Clonazepam into Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  13. ^Milgram, Anne (April 7, 2022)."Schedules of Controlled Substances: Placement of Daridorexant in Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedJanuary 16, 2023.
  14. ^Simpkins, William (August 16, 2001)."Schedules of controlled substances: Dichloralphenazone; placement into Schedule IV".VLEX.Drug Enforcement Administration.Archived from the original on January 16, 2023. RetrievedJanuary 16, 2023.
  15. ^Leonhart, Michele (October 6, 2009)."Schedules of Controlled Substances; Placement of Fospropofol Into Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedJanuary 16, 2023.
  16. ^Mullen, Jr., Francis M. (October 29, 1981)."Schedules of Controlled Substances: Placement of Halazepam in Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  17. ^Evans, D. Christopher (March 3, 2021)."Schedules of Controlled Substances: Placement of Lemborexant in Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedJanuary 16, 2023.
  18. ^Bensinger, Peter (October 7, 1977)."Placement of Lorazepam in Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  19. ^Bartels, Jr., John R. (January 30, 1975)."Placement of Mebutamate in Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2022.
  20. ^abLawn, John (March 25, 1986)."Schedules of Controlled Substances; Placement of Quazepam and Midazolam into Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  21. ^Bensinger, Peter (December 17, 1976)."Placement of Prazepam into Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  22. ^Evans, D. Christopher (July 2, 2021)."Schedules of Controlled Substances: Placement of Remimazolam in Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedSeptember 6, 2023.
  23. ^Harrigan, Thomas (August 28, 2014)."Schedules of Controlled Substances: Placement of Suvorexant into Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedJanuary 16, 2023.
  24. ^Bensinger, Peter (April 7, 1981)."Schedules of Controlled Substances; Placement of Temazepam into Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  25. ^Mullen, Jr., Francis M. (December 28, 1982)."Schedules of Controlled Substances; Placement of Triazolam into Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  26. ^Marshall, Donnie (September 15, 1999)."Schedules of Controlled Substances; Placement of Zaleplon into Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedJanuary 16, 2023.
  27. ^Bonner, Robert (February 5, 1993)."Schedules of Controlled Substances; Placement of Zolpidem into Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration. Archived fromthe original(PDF) on March 3, 2022. RetrievedJanuary 16, 2023.
  28. ^Leonhart, Michele (April 4, 2005)."Schedules of Controlled Substances: Placement of Zopiclone Into Schedule IV".Federal Register.Drug Enforcement Administration.
  29. ^Milgram, Anne (October 31, 2023)."Schedules of Controlled Substances: Placement of Zuranolone in Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedNovember 3, 2023.
  30. ^Leonhart, Michele (May 8, 2013)."Schedules of Controlled Substances: Placement of Lorcaserin Into Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedJanuary 16, 2023.
  31. ^abcdLawn, John (May 17, 1988)."Schedules of Controlled Substances; Temporary Placement of Cathine ((+ )-norpseudoephedrine), Fencamfamin, Fenproporex and Mefenorex Into Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration. Archived fromthe original(PDF) on March 3, 2022. RetrievedJanuary 16, 2023.
  32. ^abIngersoll, John (July 6, 1973)."Diethylpropion and Phentermine; Temporary Placement in Schedule IV"(PDF).Isomer Design. Bureau of Narcotics and Dangerous Drugs.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  33. ^Mullen, Jr., Francis M. (October 27, 1981)."Rescheduling of Mazindol into Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on September 26, 2021. RetrievedJanuary 16, 2023.
  34. ^Marshall, Donnie (January 27, 1999)."Schedules of Controlled Substances: Placement of Modafinil Into Schedule IV".Federal Register.Drug Enforcement Administration.
  35. ^Bartels, Jr., John R. (January 28, 1975)."Placement of Pemoline in Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  36. ^abBensinger, Peter (September 30, 1980)."Pipradrol and SPA in Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  37. ^Milgram, Anne (July 25, 2022)."Schedules of Controlled Substances: Placement of Serdexmethylphenidate in Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedSeptember 6, 2023.
  38. ^Gruden, Peter (February 11, 1998)."Schedules of Controlled Substances: Placement of Sibutramine Into Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedJanuary 16, 2023.
  39. ^Dhillon, Uttam (January 7, 2020)."Schedules of Controlled Substances: Placement of Solriamfetol in Schedule IV".Federal Register.Drug Enforcement Administration. RetrievedJanuary 16, 2023.
  40. ^Bensinger, Peter (February 9, 1979)."Placement of Pentazocine into Schedule IV"(PDF).Isomer Design.Drug Enforcement Administration.Archived(PDF) from the original on March 3, 2022. RetrievedJanuary 16, 2023.
  41. ^Milford, Jr., James S. (October 31, 1997)."Schedules of Controlled Substances Placement of Butorphanol Into Schedule IV".Federal Register.Drug Enforcement Administration.Archived from the original on January 16, 2023. RetrievedJanuary 16, 2023.
  42. ^Rosenberg, Chuck (November 12, 2015)."Schedules of Controlled Substances: Placement of Eluxadoline Into Schedule IV".Federal Register.Drug Enforcement Administration.Archived from the original on January 16, 2023. RetrievedJanuary 16, 2023.
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