Lergotrile

Clinical data
Other names	LY-79907; 2-Chloro-6-methylergoline-8β-acetonitrile
Identifiers
IUPAC name 2-[(6aR,9S,10aR)-5-chloro-7-methyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinolin-9-yl]acetonitrile
CAS Number	36945-03-6 Y
PubChemCID	6918447
ChemSpider	5293644
UNII	O68JXU1W09
KEGG	D04693
ChEMBL	ChEMBL80937
CompTox Dashboard(EPA)	DTXSID701043282
Chemical and physical data
Formula	C17H18ClN3
Molar mass	299.80 g·mol−1
3D model (JSmol)	Interactive image
SMILES CN1C[C@@H](C[C@H]2[C@H]1CC3=C(NC4=CC=CC2=C34)Cl)CC#N
InChI InChI=1S/C17H18ClN3/c1-21-9-10(5-6-19)7-12-11-3-2-4-14-16(11)13(8-15(12)21)17(18)20-14/h2-4,10,12,15,20H,5,7-9H2,1H3/t10-,12-,15-/m1/s1 Key:JKAHWGPTNVUTNB-IXPVHAAZSA-N

Lergotrile (INNTooltip International Nonproprietary Name,USANTooltip United States Adopted Name) is anergolinederivative which acts as adopamine receptor agonist. It was developed for the treatment ofParkinson's disease, but failed inclinical trials due toliver toxicity.^[1][2]

Thisdrug article relating to thenervous system is astub. You can help Wikipedia byexpanding it.

• v
• t
• e

• Chloroarenes
• Dopamine agonists
• Ergolines
• Nitriles
• Prolactin inhibitors
• Nervous system drug stubs

• Articles with short description
• Short description matches Wikidata
• Short description is different from Wikidata
• Chemical pages without DrugBank identifier
• Drugs missing an ATC code
• Drugs with no legal status
• Articles containing unverified chemical infoboxes
• All stub articles