| Clinical data | |
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| Routes of administration | IV |
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| Chemical and physical data | |
| Formula | C107H179N35O36S7 |
| Molar mass | 2756.24 g·mol−1 |
Leconotide (INN; development codesCNSB004 andAM336; also known asω-conotoxin CVID) is anω-conotoxinpeptide isolated from thevenom ofConus catus which is under investigation as ananalgesicdrug for the treatment ofpain conditions.[1][2]
It acts as anN-type voltage-gated calcium channel (Cav2.2)blocker and is highly selective for this channel over the relatedP/Q-type voltage-gated calcium channel (Cav2.1).[1][2]
Relative toziconotide, leconotide is advantageous in that it is significantly lesstoxic, and for that reason can be administeredintravenously as opposed to viaintrathecal injection.[3][4][5]
