Kuppamuthu Dharmalingam | |
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| Born | (1949-01-03)3 January 1949 (age 76) Pollachi,Tamil Nadu, India |
| Alma mater |
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| Known for | Induction ofmutagenic DNA repair inEscherichia coli Proteomics of eye diseases |
| Awards | 1992 Shanti Swarup Bhatnagar Prize |
| Scientific career | |
| Fields | |
| Institutions |
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| Doctoral advisor | J. Jayaraman |
Kuppamuthu Dharmalingam (born 3 January 1949) is an Indianproteomicist, geneticist, academic and the founder ofCentre of Excellence in Bioinformatics atMadurai Kamaraj University. He is known for his contributions in the fields of eye diseaseproteomics andmutagenic DNA repair inEscherichia coli.[1] He is an elected fellow of theIndian Academy of Sciences[2] and theNational Academy of Sciences, India.[3] TheCouncil of Scientific and Industrial Research, the apex agency of the Government of India for scientific research, awarded him theShanti Swarup Bhatnagar Prize for Science and Technology, one of the highest Indian science awards, in 1992, for his contributions to biological sciences.[4]
Born on 3 January 1949 inPollachi, a border town in theSouth Indian state ofTamil Nadu, Kuppamuthu Dharmalingam did his schooling at Gandhi Kala Nilayam High School and secured his graduate and master's degrees in zoology from Thiagarajar College,Madurai before enrolling for PhD atMadurai Kamaraj University (MKU) under the guidance of J. Jayaraman, working onyeast mitochondrial membranebiogenesis.[citation needed] After obtaining his doctoral degree, he did his post-doctoral research withEdward D. Goldberg atTufts University School of Medicine ongenetics ofbacteriophages. Returning to India, he joined MKU[5] and spent his entire academic career there but had a short stint atUniversity of Geneva in between. During his early researches onEscherichia coli, agram-negative bacterium, he discovered theinduction of mutagenic DNA repair during restriction of nonglucosylated T4 DNA and thealleviation of restriction by SOS functions.[6] Subsequently, he studied thepathogenesis ofMycobacterium leprae usingproteomics tools and discovered thesingle nucleotide polymorphism in the unique small alpha crystalline like heat shock protein in thegram-positive bacterium.[7] His researches have been documented in over 200 articles;ResearchGate, an online repository of scientific papers, has listed 48 of them.[8]
It was during his tenure at the MKU, theCentre of Excellence in Bioinformatics was established at the university in 1986.[citation needed] He is a life member of the Proteomics Society, India (PSI),[9] editor of its newsletter,[10] a former member of its executive council and was the convener of the workshop,Clinical Proteomics: Methods and Applications, conducted by PSI in October 2014.[11] He is a Distinguished Research Professor of theDepartment of Biotechnology and an elected fellow of theIndian Academy of Sciences[2] and theNational Academy of Sciences, India.[3] TheCouncil of Scientific and Industrial Research awarded him theShanti Swarup Bhatnagar Prize, one of the highest Indian science awards, in 1992.[4]
Post retirement, Dharmalingam has been working since 2013 as a director of Aravind Medical Research Foundation, a Tamil Nadu-based research centre, ophthalmic hospital chain and aWorld Health Organization collaborating centre for the prevention of blindness.[12]
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