Karen Radner started her studies at theUniversity of Vienna in 1990 in Ancient Near Eastern Languages and Archaeology. She graduated in 1994 with an MA (summa cum laude) and 1997 with a PhD (summa cum laude).[2] Her doctoral work was titledDie neuassyrischen Privatrechtsurkunden als Quelle für Mensch und Umwelt ("The Neo-Assyrian Private Legal Documents as Source for Mankind and Environment"). This study was published in 1997 as part of theState Archives of Assyria Studies Series (Vol. 6) based at theUniversity of Helsinki.
Following her doctoral studies, Radner spent two years in theUniversity of Helsinki as a junior research fellow (1997-1999) and one year at theUniversity of Tübingen as a research fellow (1999). In 1999, Radner moved to theUniversity of Munich as a research assistant and started herHabilitation, which was completed in 2004 and is entitled "Die Macht des Namens. Altorientalische Strategien zur Selbsterhaltung" ("The Power of a Name: Ancient Near Eastern Strategies for Self-Preservation"). This was published in 2005. From 2005-2015, Radner worked atUniversity College London as a lecturer, reader, and then professor in Ancient Near Eastern History. During this time, she was also a guest professor at theUniversity of Verona, theUniversity of Innsbruck, UCL Qatar, Doha, andKoç University, Istanbul.
In 2016, Radner was elected to the Bayerische Akademie der Wissenschaften (Bavarian Academy of Sciences and Humanities). Since 2015, Radner has also been an Honorary Professor of Ancient Near Eastern History at University College London.
Die neuassyrischen Privatrechtsurkunden als Quelle für Mensch und Umwelt (= State archives of Assyria studies. Band 6). Neo-Assyrian Text Corpus Project, Helsinki 1997,ISBN951-45-7783-3 (zugleich Dissertation, Wien 1997).
The Prosopography of the Neo-Assyrian Empire 1/I: A. Neo-Assyrian Text Corpus Project, Helsinki 1998,ISBN951-45-8163-6.
The Prosopography of the Neo-Assyrian Empire 1/II. B–G. Neo-Assyrian Text Corpus Project, Helsinki 1999,ISBN978-951-45-8645-3.
Ein neuassyrisches Privatarchiv der Tempelgoldschmiede von Assur (= Studien zu den Assur-Texten. Band 1). Saarbrücker Druckerei und Verlag, Saarbrücken 1999,ISBN3-930843-44-7 (zugleich Diplomarbeit, Wien 1994).
Neuassyrische Rechtsurkunden II (= Wissenschaftliche Veröffentlichungen der Deutschen Orient-Gesellschaft. Band 98). Hinrichs, Leipzig 2000,ISBN3-930843-58-7.
Die neuassyrischen Texte aus Tall Šēḫ Ḥamad (= Berichte der Ausgrabung Tall Šēḫ Ḥamad/Dūr-Katlimmu. Band 6). Reimer, Berlin 2002,ISBN3-496-02746-0.
Das mittelassyrische Tontafelarchiv von Giricano, Dunnu-sa-Uzibi (= Subartu. Band 14). Brepols, Turnhout 2004,ISBN2-503-51581-9.
Die Macht des Namens. Altorientalische Strategien zur Selbsterhaltung (= SANTAG – Arbeiten und Untersuchungen zur Keilschriftskunde. Band 8). Harrassowitz, Wiesbaden 2005,ISBN3-447-05328-3 (zugleich Habilitationsschrift, München 2004).
as editor with Eleanor Robson: The Oxford Handbook of Cuneiform Culture. Oxford University Press, Oxford 2011,ISBN978-0-19-955730-1.
as editor: State Correspondences of the Ancient World from the New Kingdom to the Roman Empire. From New Kingdom Egypt to the Roman Empire (= Oxford Studies in Early Empires). Oxford University Press, Oxford 2014,ISBN978-0-19-935477-1.
Ancient Assyria (= Very short introductions. Stimulating ways in to new subjects. Band 424). Oxford University Press, Oxford 2015,ISBN978-0-19-871590-0.
with Peter A. Miglus and Franciszek M. Stępniowski: Ausgrabungen in Assur: Wohnquartiere in der Weststadt, Teil I (= Wissenschaftliche Veröffentlichungen der Deutschen Orient-Gesellschaft. Band 152). Harrassowitz, Wiesbaden 2016,ISBN978-3-447-10742-6.
as editor with Florian Janoscha Kreppner and Andrea Squitieri: Exploring the Neo-Assyrian Frontier with Western Iran: The 2015 Season at Gird-i Bazar andQalat-i Dinka (= Peshdar Plain Project Publications. Band 1). PeWe-Verlag, Gladbeck 2016,ISBN3-935012-20-9 (online).
as editor with Florian Janoscha Kreppner and Andrea Squitieri: Unearthing the Dinka Settlement Complex: The 2016 Season at Gird-i Bazar and Qalat-i Dinka (= Peshdar Plain Project Publications. Band 2). PeWe-Verlag, Gladbeck 2017,ISBN978-3-935012-28-7 (online).
Mesopotamien. Die frühen Hochkulturen an Euphrat und Tigris. Beck, München 2017,ISBN3-406-71406-4.
The Oxford History of the Ancient Near East: From the Beginnings to Old Kingdom Egypt and the Dynasty of Akkad (multi volume series, 2020—2024, co-editor withDaniel T. Potts andNadine Moeller).