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KIF9

From Wikipedia, the free encyclopedia
Motor protein found in humans

KIF9
Available structures
PDBOrtholog search:PDBeRCSB
List of PDB id codes

3NWN

Identifiers
AliasesKIF9, kinesin family member 9
External IDsOMIM:607910;MGI:1098237;HomoloGene:65620;GeneCards:KIF9;OMA:KIF9 - orthologs
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for KIF9
Genomic location for KIF9
Band3p21.31Start47,227,998bp[1]
End47,283,451bp[1]
Gene location (Mouse)
Chromosome 9 (mouse)
Chr.Chromosome 9 (mouse)[2]
Chromosome 9 (mouse)
Genomic location for KIF9
Genomic location for KIF9
Band9|9 F2Start110,306,026bp[2]
End110,354,247bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • bronchial epithelial cell

  • sperm

  • caput epididymis

  • left testis

  • mucosa of paranasal sinus

  • right testis

  • right uterine tube

  • olfactory zone of nasal mucosa

  • tendon of biceps brachii

  • corpus epididymis
Top expressed in
  • spermatid

  • spermatocyte

  • seminiferous tubule

  • olfactory epithelium

  • choroid plexus of lateral ventricle

  • choroid plexus of fourth ventricle

  • Epithelium of choroid plexus

  • vestibular sensory epithelium

  • oocyte

  • primary oocyte
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
Cellular component
Biological process
Sources:Amigo /QuickGO
Orthologs
SpeciesHumanMouse
Entrez

64147

16578

Ensembl

ENSG00000088727

ENSMUSG00000032489

UniProt

Q9HAQ2
Q6PJI1

Q9WV04

RefSeq (mRNA)
NM_001134878
NM_022342
NM_182902
NM_182903
NM_001377474

NM_001377475
NM_001377476
NM_001377477

NM_001163569
NM_010628

RefSeq (protein)
NP_001128350
NP_071737
NP_878905
NP_001364403
NP_001364404

NP_001364405
NP_001364406

NP_001157041
NP_034758

Location (UCSC)Chr 3: 47.23 – 47.28 MbChr 9: 110.31 – 110.35 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Kinesin family member 9 (KIF9), also known as kinesin-9, is ahumanprotein encoded by the KIF9gene. It is part of thekinesin family ofmotor proteins.

Function

[edit]

The beating of theflagella insperm is regulated by KIF9 activity.[5]

References

[edit]
  1. ^abcGRCh38: Ensembl release 89: ENSG00000088727Ensembl, May 2017
  2. ^abcGRCm38: Ensembl release 89: ENSMUSG00000032489Ensembl, May 2017
  3. ^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^Miyata H, Shimada K, Morohoshi A, Oura S, Matsumura T, Xu Z, et al. (April 2020)."Testis-enriched kinesin KIF9 is important for progressive motility in mouse spermatozoa".FASEB Journal.34 (4):5389–5400.doi:10.1096/fj.201902755R.PMC 7136151.PMID 32072696.
Human
Microfilaments
andABPs
Myofilament
Actins
Myosins
Other
Other
Intermediate
filaments
Type 1/2
(Keratin,
Cytokeratin)
Epithelial keratins
(soft alpha-keratins)
Hair keratins
(hard alpha-keratins)
Ungrouped alpha
Not alpha
Type 3
Type 4
Type 5
Microtubules
andMAPs
Tubulins
MAPs
Kinesins
Dyneins
Microtubule organising proteins
Microtubule severing proteins
Other
Catenins
Membrane
Other
Nonhuman


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