Potassium inwardly-rectifying channel, subfamily J, member 8, also known asKCNJ8, is a humangene encoding theKir6.1protein.[5] Amutation in KCNJ8 has been associated withcardiac arrest in the early repolarization syndrome.
Potassium channels are present in mostmammalian cells, where they participate in a wide range of physiologic responses. Kir6.1 is an integralmembrane protein and inward-rectifier type potassium channel. Kir6.1, which has a greater tendency to allowpotassium to flow into a cell rather than out of a cell, is controlled byG-proteins.[5]
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