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KCNJ13

Українська

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From Wikipedia, the free encyclopedia

Protein-coding gene in the species Homo sapiens

KCNJ13

Identifiers

Aliases

KCNJ13, KIR1.4, KIR7.1, LCA16, SVD, potassium voltage-gated channel subfamily J member 13, potassium inwardly rectifying channel subfamily J member 13

External IDs

OMIM:603208;MGI:3781032;HomoloGene:55638;GeneCards:KCNJ13;OMA:KCNJ13 - orthologs

Gene location (Human)

Chr.	Chromosome 2 (human)^[1]

Band	2q37.1	Start	232,765,802bp^[1]
Band	2q37.1	End	232,776,565bp^[1]

Gene location (Mouse)

Chr.	Chromosome 1 (mouse)^[2]

Band	1 D\|1	Start	87,314,085bp^[2]
Band	1 D\|1	End	87,322,451bp^[2]

RNA expression pattern

Bgee

Human

Mouse (ortholog)

Top expressed in

Epithelium of choroid plexus

retinal pigment epithelium

jejunal mucosa

testicle

buccal mucosa cell

sural nerve

mucosa of ileum

Achilles tendon

duodenum

bone marrow cells

Top expressed in

Epithelium of choroid plexus

retinal pigment epithelium

iris

otolith organ

utricle

ciliary body

sciatic nerve

olfactory epithelium

stria vascularis

vestibular membrane of cochlear duct

More reference expression data

BioGPS


More reference expression data

Gene ontology
Molecular function	inward rectifier potassium channel activity voltage-gated ion channel activity
Cellular component	integral component of membrane integral component of plasma membrane membrane
Biological process	potassium ion transport regulation of ion transmembrane transport ion transport potassium ion import across plasma membrane
Sources:Amigo /QuickGO

Orthologs

Species

Human

Mouse

Entrez


3769


100040591

Ensembl


ENSG00000115474


ENSMUSG00000079436

UniProt


O60928


P86046

RefSeq (mRNA)


NM_002242 NM_001172416 NM_001172417


NM_001110227

RefSeq (protein)


NP_001165887 NP_001165888 NP_002233


NP_001103697

Location (UCSC)

Chr 2: 232.77 – 232.78 Mb

Chr 1: 87.31 – 87.32 Mb

PubMed search

^[3]

^[4]

Wikidata

View/Edit Human

View/Edit Mouse

Potassium inwardly-rectifying channel, subfamily J, member 13 (KCNJ13) is a humangene encoding theK_ir7.1protein.^[5]

References

[edit]

^^a ^b ^cGRCh38: Ensembl release 89: ENSG00000115474 –Ensembl, May 2017
^^a ^b ^cGRCm38: Ensembl release 89: ENSMUSG00000079436 –Ensembl, May 2017
^"Human PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:".National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Entrez Gene: KCNJ13 potassium inwardly-rectifying channel, subfamily J, member 13".

External links

[edit]

KCNJ13+protein,+human at the U.S. National Library of MedicineMedical Subject Headings (MeSH)

Thismembrane protein–related article is astub. You can help Wikipedia byexpanding it.

This article incorporates text from theUnited States National Library of Medicine, which is in thepublic domain.

Membrane transport protein:ion channels (TC 1A)

Ca²⁺:Calcium channel

Ligand-gated	Inositol trisphosphate receptor 1 2 3 Ryanodine receptor 1 2 3
Voltage-gated	L-type/Ca_vα 1.1 1.2 1.3 1.4 N-type/Ca_vα2.2 P-type/Ca_vα 2.1 Q-type/Ca_vα2.1 R-type/Ca_vα2.3 T-type/Ca_vα 3.1 3.2 3.3 α₂δ-subunits 1 2 β-subunits β1 β2 β3 β4 γ-subunits γ1 γ2 γ3 γ4 Cation channels of sperm 1 2 3 4 Two-pore channel 1 2

Na⁺:Sodium channel

Constitutively active	Epithelial sodium channel α β γ δ
Proton-gated	Amiloride-sensitive cation channel 1 2 3 4
Voltage-gated	Na_vα 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 7A Na_vβ 1 2 3 4

K⁺:Potassium channel

Calcium-activated	BK channel α1 β1 β2 β3 β4 SK channel SK1 SK2 SK3 IK channel IK1 K_Ca 1.1 2.1 2.2 2.3 3.1 4.1 4.2 5.1
Inward-rectifier	K_ATP K_ir 1.1 2.1 2.2 2.3 2.4 2.6 GIRK/K_ir 3.1 3.2 3.3 3.4 K_ir 4.1 4.2 5.1 6.1 6.2 7.1
Tandem pore domain	K2P 1 2 3 4 5 6 7 9 10 12 13 15 16 17 18
Voltage-gated	K_vα1-6 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 2.1 2.2 3.1 3.2 3.3 3.4 4.1 4.2 4.3 5.1 6.1 6.2 6.3 6.4 K_vα7-12 7.1 7.2 7.3 7.4 7.5 8.1 8.2 9.1 9.2 9.3 10.1 10.2 11.1/hERG 11.2 11.3 12.1 12.2 12.3 K_vβ 1 2 3 KCNIP 1 2 3 4 minK/ISK minK/ISK-like MiRP 1 2 3 Shaker (gene)

Miscellaneous

Cl⁻:Chloride channel	Calcium-activated chloride channels Anoctamin ANO1 Bestrophin 1 2 Chloride Channel Accessory 1 2 3 4 CFTR CLCN 1 2 3 4 5 6 7 KA KB CLIC 1 2 3 4 5 6 L1 CLNS 1A 1B
H⁺:Proton channel	HVCN1
M⁺:CNG cation channel	α 1 2 3 4 β 1 2 3 HCN FC 1 2 3 4
M⁺:TRP cation channel	TRPA (1) TRPC 1 2 3 4 4AP 5 6 7 TRPM 1 2 3 4 5 6 7 8 TRPML 1 2 3 TRPN TRPP 1 2 TRPV 1 2 3 4 5 6
H₂O (+solutes):Porin	Aquaporin 0 1 2 3 4 5 6 7 8 9 Voltage-dependent anion channel 1 2 3 General bacterial porin family
Cytoplasm:Gap junction	Connexin A GJA1 GJA3 GJA4 GJA5 GJA8 GJA9 GJA10 B GJB1 GJB2 GJB3 GJB4 GJB5 GJB6 GJB7 C GJC1 GJC2 GJC3 D GJD2 GJD3 GJD4 Innexin