Myers redshirted his true freshman season as he moved from guard to center.[4] He played in ten games as a redshirt freshman as the backup to starting centerMichael Jordan.[5][6] Myers was named the starting center going into his redshirt sophomore season.[7][8] He played over 900 offensive snaps and was named second-teamAll-Big Ten Conference by the league's coaches.[9] Myers was named a team captain going into his redshirt junior year.[10]
On April 30, 2021, Myers was selected in the second round (62nd overall) by theGreen Bay Packers in the2021 NFL draft.[13] He signed his four-year rookie contract on May 14, 2021,[14] worth $5.58 million, including a $1.41 million signing bonus.[15]
Myers was named the Packers starting center as a rookie, replacingAll-Pro centerCorey Linsley who had left for theLos Angeles Chargers. Myers started five games before suffering a knee injury in Week 6. He was placed oninjured reserve on October 23, 2021.[16] He was activated off injured reserve on January 8, 2022.[17] At the end of the 2024 season, Myers was named the Packers recipient of theEd Block Courage award after missing only one game despite battling wrist and pectoral injuries.[18]
On March 14, 2025, Myers signed a one-year, $3.5 million contract with theNew York Jets.[19] On December 12, Myers signed a two-year, $11 million contract extension with the Jets.[20]